Bionomics | Investor Presentation Deck | 59 slides

Bionomics · 2022-10
arc beats above · slides in the middle · loops below · scroll → 3 LOOPS
SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
HOVER FOR DETAILS · CLICK A SLIDE FOR FULLSCREEN · STEP 2
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Slide inventory

59
every slide · same image gating as the playbook
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Slide 1
The brain graphic is a stylized circuit board, representing the intersection of neuroscience and technology.front_matter
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front_matter
Open slide detailBeat · Problem
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SAD stands for Social Anxiety Disorder. The slide uses a metaphorical illustration of a person being scrutinized under a magnifying glass.frame_problem
Open slide detailBeat · Problem
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Speed Bump cartoon by Dave Coverly, 2011.filler
Open slide detailBeat · Problem
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The slide uses a yellow callout box to provide context for the quote.other
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Data source: Kessler RC et al. Arch Gen Psychiatry 2005;62:593-602 and 617-627.size_opportunity
Open slide detailBeat · Market Size
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The slide highlights Social Anxiety Disorder in red text.size_opportunity
Open slide detailBeat · Market Size
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The slide provides prevalence statistics and demographic correlations for SAD.establish_context
Open slide detailBeat · Market Size
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The slide uses a tree-like structure to categorize various mental health conditions under the umbrella of Anxiety Disorders, while also showing related categoriestablish_context
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The slide uses a humorous illustration to emphasize the common fear of public speaking.other
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SAD stands for Social Anxiety Disorder.establish_context
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The slide uses a complex overlapping circle diagram to map psychiatric conditions. Source: Stein MB & Stein DJ. Lancet 2008.present_framework
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The slide uses a complex overlapping circle diagram to map psychiatric conditions. Source: Stein MB & Stein DJ. Lancet 2008.establish_context
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The slide outlines a standard clinical decision-making process for pharmacotherapy.present_framework
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SAD likely refers to Social Anxiety Disorder. The image uses a metaphor of a single red figure facing a group of multi-colored figures.establish_context
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The slide illustrates the 'Approach' side of the conflict; the 'Avoidance' side is implied by the context of SAD.frame_problem
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SAD likely stands for Social Anxiety Disorder. The diagram uses a circular flow to represent the internal conflict.establish_context
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summarize
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Includes UC San Diego Health branding.front_matter
Open slide detailBeat · Solution
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present_solution
Open slide detailBeat · Solution
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The slide displays a snippet of the LSAS questionnaire, showing the scoring criteria for 'Fear or Anxiety' and 'Avoidance' and providing examples of the 24 itempresent_framework
Open slide detailBeat · Solution
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frame_problem
Open slide detailBeat · Solution
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The slide uses a circular crop for the image, which is a common design element in pitch decks to create visual interest.present_solution
Open slide detailBeat · Solution
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The slide uses a nested bulleted list to define the three core components of a behavioral challenge.establish_context
Open slide detailBeat · Solution
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establish_context
Open slide detailBeat · Solution
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BNC210 refers to the Trier Social Stress Test (TSST) or a variant thereof used in clinical research.establish_context
Open slide detailBeat · Solution
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The slide details the constraints of the experiment: 5 topics, 2 min prep, 5 min speech, and 3 audience members.present_solution
Open slide detailBeat · Solution
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This is a standard clinical measurement tool for anxiety and distress levels.present_framework
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The table maps specific time intervals (pre-dose, resting, preparation, performance, post-challenge) to data collection points.present_framework
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The table highlights the 'Public Speaking Challenge - Performance' phase with a purple border.plan_implementation
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The chart displays data from Bergamaschi et al. (2011) regarding acute CBD treatment for Social Anxiety Disorder (SAD).analyze_data
Open slide detailBeat · Traction
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The chart highlights the efficacy of CBD in reducing anxiety during the 'A' (Anticipation) and 'S' (Speaking) phases of the challenge.show_traction
Open slide detailBeat · Traction
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The chart highlights a statistically significant difference between CBD and Placebo groups during the speaking phase.analyze_data
Open slide detailBeat · Traction
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The chart highlights the performance phase where the PH94B group shows a downward trend in distress compared to the placebo group.show_traction
Open slide detailBeat · Traction
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The slide uses a hierarchical list to detail the research methodology.present_framework
Open slide detailBeat · Traction
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The chart highlights the 'Speech' phase with a box. SUDS is a standard clinical measure for anxiety.show_traction
Open slide detailBeat · Traction
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summarize
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front_matter
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The slide uses a list-based layout with icons to summarize key company highlights.summarize
Open slide detailLoop · Pareto Focus
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Includes a legend for FDA Fast Track designation and definitions for NAM/PAM.plan_implementation
Open slide detailLoop · Pareto Focus
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Includes a detailed biological process diagram and a conceptual model of disease state vs. normalized state.present_solution
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The table lists 13 rows, though the title mentions 12 trials; likely one trial is split or there is a discrepancy in the count.show_traction
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The table uses checkmarks and X marks to denote presence or absence of specific clinical benefits/side effects.compare_peers
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The right-hand diagram is a stylized funnel/segmentation representation of the addressable market.size_opportunity
Open slide detailLoop · Quick Win Big Bet
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The slide uses a pharmacokinetic line chart to demonstrate rapid absorption and a bulleted list to summarize clinical efficacy in GAD and panic models.present_solution
Open slide detailLoop · Quick Win Big Bet
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The slide uses a bar chart to compare placebo vs BNC210 across two metrics: total number of symptoms and symptom intensity.show_traction
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The slide outlines a specific clinical trial protocol involving 24 GAD patients.plan_implementation
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Includes references to specific clinical studies and behavioral tasks (JORT).show_traction
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The slide uses a process flow diagram to illustrate the clinical trial methodology.plan_implementation
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The slide details the research rigor behind the market sizing/revenue projections.analyze_data
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The slide uses a flow-chart style to represent patient movement between treatment lines.establish_context
Open slide detailLoop · Cost Of Inaction
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Includes qualitative feedback from psychiatrists alongside key findings.show_traction
Open slide detailLoop · Cost Of Inaction
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Includes qualitative testimonials from psychiatrists to support the adoption thesis.show_traction
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The slide uses a hierarchical decomposition framework to show how revenue is derived from epidemiological and commercial assumptions.present_framework
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The chart displays a steady growth trajectory for the drug's revenue.size_opportunity
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The slide uses a list-based framework to highlight five key pillars of the drug's value proposition.present_solution