NeuroSense Therapeutics | Investor Presentation Deck | 33 slides

NeuroSense Therapeutics · 2024-01
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SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
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33
every slide · same image gating as the playbook
01
Slide 1
Features a 3D rendering of a synapse.front_matter
03
summarize
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The slide uses a standard pharmaceutical pipeline visualization (Discovery to NDA).plan_implementation
05
Includes a personal testimonial/case study image of a patient (Shay) to humanize the disease.frame_problem
Open slide detailBeat · Problem
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The slide uses a biological mechanism-of-action illustration to show how the drug components interact with specific cellular stressors.present_solution
Open slide detailBeat · Solution
07
The slide uses a combination of a biological mechanism diagram and a pharmacokinetic line chart to prove efficacy.present_solution
Open slide detailBeat · Solution
08
Includes a process diagram for iPSC generation and two charts: a survival curve and a hazard ratio bar chart.show_traction
Open slide detailBeat · Solution
09
The chart demonstrates that PrimeC aligns the peak concentrations of two different drugs, which is the core value proposition of their formulation technology.present_solution
Open slide detailBeat · Solution
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Study identifier NST002, 15 patients, open-label, intermediate formulation.show_traction
Open slide detailBeat · Solution
11
Includes details on screen failures and co-treatment with Riluzole.plan_implementation
Open slide detailBeat · Solution
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Uses numbered icons for primary/secondary and a lightbulb icon for exploratory.present_framework
Open slide detailBeat · Solution
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Includes a footnote citation for the methodology definitions.analyze_data
Open slide detailBeat · Solution
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other
Open slide detailBeat · Solution
15
The slide shows baseline characteristics for a clinical trial, confirming that the treatment and placebo groups are well-matched.analyze_data
Open slide detailBeat · Solution
16
The table displays percentages for various categories of adverse events (AEs) and treatment-emergent adverse events (TEAEs).show_traction
Open slide detailBeat · Solution
17
The slide highlights a statistically significant 37.4% reduction in disease progression for the Per Protocol population, while noting a 29% reduction (p=0.12) fshow_traction
Open slide detailBeat · Solution
18
The slide uses icons to represent functional domains and provides specific clinical examples of what a 1-point change means for patient quality of life.establish_context
Open slide detailBeat · AgitateLoop · Cost Of Inaction
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The chart visualizes the reduction in point loss, highlighting the efficacy of PrimeC.show_traction
Open slide detailBeat · AgitateLoop · Cost Of Inaction
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The slide uses a human silhouette to categorize ALS symptoms into four domains, then presents bar charts for each domain comparing treatment vs placebo.show_traction
Open slide detailBeat · AgitateLoop · Cost Of Inaction
21
The chart highlights a 17.2% attenuation in the decline of SVC scores for the PrimeC group compared to placebo.show_traction
22
The slide uses a series of blue blocks to represent different research pillars/methodologies within the PARADIGM trial.present_solution
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The slide uses a case study to validate the business model of combination therapies.cite_precedent
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summarize
Open slide detailBeat · Market Size
25
The slide presents clinical biomarker data comparing control vs AD groups across 6 different markers, using Mann-Whitney U tests for significance.show_traction
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The slide outlines the RoAD study parameters including patient population, dosing, and primary/secondary endpoints.present_framework
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The slide uses a grid layout to display five key advisors with their respective credentials and logos of their affiliated institutions.other
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The slide uses a grid layout to present institutional and corporate partners.other
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plan_implementation
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Slide 30 of the deck.state_next_steps
Open slide detailLoop · Quick Win Big Bet
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The chart shows a clear divergence between the treatment and placebo arms over time, with a 29.2% difference at the 180-day mark.show_traction
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The chart shows a divergence in SVC decline between the treatment and placebo groups over time.show_traction
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Data includes adjusted means, 95% confidence intervals, p-values, and percentage differences for various motor and respiratory domains.analyze_data