Exscientia | Results Presentation Deck | 24 slides

Exscientia · 2023-11
arc beats above · slides in the middle · loops below · scroll → 2 LOOPS
SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
HOVER FOR DETAILS · CLICK A SLIDE FOR FULLSCREEN · STEP 1
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24
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01
Slide 1
front_matter
Open slide detailBeat · Setup
02
other
Open slide detailBeat · Setup
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summarize
Open slide detailBeat · Setup
04
present_solution
Open slide detailBeat · EvidenceLoop · Logic Chain
05
The chart uses a horizontal bar format to represent development stages.present_solution
Open slide detailBeat · EvidenceLoop · Logic Chain
06
front_matter
Open slide detailBeat · EvidenceLoop · Logic Chain
07
Uses MIDD (Model-informed drug development) as a strategic framework for clinical progression.plan_implementation
Open slide detailBeat · EvidenceLoop · Logic Chain
08
The slide uses a human anatomy diagram to map specific patient counts to disease locations.size_opportunity
Open slide detailBeat · EvidenceLoop · Logic Chain
09
present_solution
Open slide detailBeat · EvidenceLoop · Logic Chain
10
The slide uses a process flow to show the mechanism of action for a drug candidate.present_solution
Open slide detailBeat · EvidenceLoop · Before After
11
The slide contrasts irreversible inhibition (depletion) with reversible inhibition (recovery).analyze_data
Open slide detailBeat · EvidenceLoop · Before After
12
The slide includes two charts: a line chart showing tumour volume over time and a dot plot showing plasma pro-GRP concentration reduction.analyze_data
Open slide detailBeat · EvidenceLoop · Before After
13
The slide uses box plots for aggregate data and line charts for individual patient sample responses, categorized by differentiation level.analyze_data
Open slide detailBeat · Evidence
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The slide uses a heatmap to visualize synergy (green) vs no synergy (light green) across different drug combinations.analyze_data
Open slide detailBeat · Evidence
15
Includes a heatmap showing synergy scores and two dose-response line charts demonstrating enhanced inhibition in combination treatments.analyze_data
Open slide detailBeat · Evidence
16
front_matter
17
Data shows significant synergistic effects in both models, with OCI-Ly10 showing regression and TMD8 showing synergy despite ibrutinib monotherapy inactivity.analyze_data
18
The slide shows dose-response curves for 11 patient samples. The left chart shows significant inhibition of CLL cells (IC50 0.4 µM), while the right chart showsanalyze_data
19
The table uses a heatmap-style color coding (red for high risk, green for low risk) to visualize safety metrics.compare_peers
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transition
Open slide detailBeat · Key Messages
21
Uses a concentric circle diagram to represent the layers of value (Pipeline, Financial, Strategic).present_framework
Open slide detailBeat · Key Messages
22
Includes footnote regarding fixed term bank deposits and currency basis.analyze_data
Open slide detailBeat · Key Messages
23
summarize
Open slide detailBeat · Key Messages
24
This is a standard corporate contact/disclaimer slide.state_next_steps