Exscientia | Investor Presentation Deck | 69 slides

Exscientia · 2023-10
arc beats above · slides in the middle · loops below · scroll → 2 LOOPS
SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
HOVER FOR DETAILS · CLICK A SLIDE FOR FULLSCREEN · STEP 5
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Slide inventory

69
every slide · same image gating as the playbook
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Slide 1
transition
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inspire_vision
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The slide uses a 3x2 grid layout to present quantitative achievements.show_traction
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The slide uses a dual-track timeline approach, separating pipeline progress from platform/corporate advancements.show_traction
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The slide uses a simple additive visual metaphor to represent the partnership.show_traction
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frame_problem
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The slide uses a hub-and-spoke style diagram to show how different technical capabilities feed into and are informed by precision medicine.present_solution
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The slide highlights the unique value proposition of each drug candidate in the pipeline.present_solution
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The chart uses a horizontal bar format to indicate development stage (all currently in Phase 1/2).plan_implementation
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The diagram is a concentric circle model representing value layers.present_solution
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The slide uses a stepped arrow timeline to illustrate progression from simple small molecule design to complex biological automation.plan_implementation
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Includes footnote regarding fixed term bank deposits and shares outstanding.analyze_data
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transition
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The slide uses a complex flow diagram combining a linear process with two internal feedback loops (Active Learning).present_solution
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The slide uses a circular process flow to represent a proprietary R&D pipeline.present_solution
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The slide uses a process flow diagram to illustrate a specific patient success story.illustrate_case
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The slide uses Kaplan-Meier curves to demonstrate clinical efficacy of the platform's drug prioritization.show_traction
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The slide uses a horizontal process-like layout to showcase four distinct technical pillars.present_solution
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The slide uses a circular flow diagram to represent the integration of AI and experimental biology.present_solution
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The diagram illustrates a flywheel-like process of data integration leading to target identification.present_solution
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22
The chart is a hierarchical clustering heatmap, commonly used in bioinformatics to show differential gene expression or patient response profiles.frame_problem
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The slide illustrates a computational drug discovery workflow.present_solution
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24
The diagram uses a hub-and-spoke model to show data integration, followed by a funnel for molecule generation and a circular feedback loop for active learning.present_solution
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25
The slide features a 3D molecular visualization and a UI overlay representing various drug discovery parameters (Potency, Selectivity, etc.).present_solution
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26
The scatter plot highlights a specific cluster of compounds selected by the AI that deviate from the standard Pareto front.present_solution
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The slide uses a small multiples approach to show dose-response curves across multiple patient samples, followed by a summary plot comparing the two groups overanalyze_data
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transition
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The title appears cut off at the bottom of the slide.present_solution
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The slide features a 3D molecular visualization of the inhibitor.show_traction
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31
The slide outlines a standard clinical trial progression from dose escalation to expansion, with a focus on establishing RP2D and evaluating ORR.plan_implementation
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32
The slide uses a human anatomy diagram to map specific cancer types to their respective organ systems.size_opportunity
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Includes a biological pathway diagram and a honeycomb-style indication map.size_opportunity
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34
The slide uses a three-column layout to define the target product profile (TPP) criteria.present_solution
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The table uses a color-coded heatmap (green/yellow/red) to indicate performance against criteria.compare_peers
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36
The slide presents preclinical efficacy data for a CDK7 inhibitor ('617) in ovarian (OVCAR3) and triple-negative breast cancer (HCC70) models.show_traction
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37
The main chart is a waterfall plot showing drug response scores across many samples. The right side details translational findings and a combination testing frashow_traction
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38
The slide uses a heatmap to visualize synergy (green) vs no synergy (light green) across different drug combinations and patient samples.show_traction
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39
Uses a Venn diagram to illustrate overlap between peripheral blood and tumour gene expression data.present_solution
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The slide features a 3D molecular visualization.show_traction
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The slide uses a bar chart to demonstrate efficacy at lower doses compared to a failed large pharma drug.show_traction
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The slide uses a heatmap-style table to visualize performance metrics, highlighting the competitive advantage of the company's lead asset.compare_peers
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43
The slide outlines a workflow from experimental data collection to AI-driven design and final compound nomination.present_solution
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44
The background features a 3D molecular visualization, likely representing the LSD1 protein or the drug binding to it.plan_implementation
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The slide uses a human anatomy diagram to map specific patient counts to disease locations.size_opportunity
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present_solution
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Includes two scientific citations for the mechanism and brain penetration.present_solution
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48
The slide uses a three-column layout to define the technical requirements for a drug candidate.present_solution
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49
The slide uses a color-coded heatmap to visualize performance against a Target Product Profile (TPP).compare_peers
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The slide uses a linear process flow to explain a complex computational chemistry workflow.present_solution
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51
The chart uses a Pareto front to illustrate the trade-off between CNS score and Potency, highlighting that the 'best' molecules are not always the most informatpresent_solution
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Includes statistical significance markers (*) on the tumour volume chart.show_traction
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The slide uses two distinct chart types (dot plot and line chart) to demonstrate safety profiles.present_solution
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The chart shows tumour volume over time for various dosing regimens compared to a vehicle control.present_solution
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present_solution
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The slide uses a split-layout to contrast current operational status with overall program value proposition.summarize
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The slide uses a stylized molecular visualization as a background element.plan_implementation
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The slide uses a three-column layout to summarize the value proposition of the drug candidate.present_solution
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frame_problem
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present_solution
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present_solution
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The slide uses a heatmap-style table to compare performance against criteria. The UGT1A1 row is highlighted to emphasize the competitive advantage.compare_peers
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63
The slide outlines a multi-stage pipeline: Initiate, Analyse, Evolve, 2D Models, 3D Models, and Active Learning.present_solution
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64
The image shows a protein binding site with color-coded regions (Donor, Apolar, Acceptor) indicating chemical properties.present_solution
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The chart shows dose-dependent tumour volume reduction over time compared to vehicle.show_traction
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The chart shows tumour volume over time (D20-D30). The combination arm (teal) shows a flat line compared to the growth seen in monotherapy and vehicle arms.present_solution
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present_solution
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summarize
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This is a standard corporate contact/disclaimer slide.appendix
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