RayzeBio | IPO Presentation Deck | 41 slides

RayzeBio · 2023-09
arc beats above · slides in the middle · loops below · scroll → 3 LOOPS
SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
HOVER FOR DETAILS · CLICK A SLIDE FOR FULLSCREEN · STEP 2
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Slide inventory

41
every slide · same image gating as the playbook
01
Slide 1
front_matter
03
This is a standard IPO/follow-on offering summary table.plan_implementation
04
The slide uses a structured table format to present key company metrics and status.summarize
05
present_solution
06
The slide uses a Gantt-style visualization for drug development stages.plan_implementation
07
Uses a visual metaphor of 'Outside in' vs 'Precise from within' to contrast the two treatment modalities.compare_peers
08
The slide uses a simple comparison framework to highlight clinical benefits.compare_peers
09
The slide uses a comparison framework to justify the use of alpha-emitting isotopes in targeted radiotherapy.frame_problem
Open slide detailBeat · Problem
10
The slide uses a chronological progression of therapeutic classes (Targeted, Immuno-oncology, ADCs, Cell Therapy) leading to RPT.argue_timing
Open slide detailBeat · ProblemLoop · Why Now
11
The slide uses a comparison table to validate the market potential of the radiopharmaceutical space by highlighting a competitor's success.show_traction
Open slide detailBeat · ProblemLoop · Why Now
12
The slide uses a process flow diagram to show the standard of care progression for two types of NETs.frame_problem
Open slide detailBeat · ProblemLoop · Cost Of Inaction
13
The slide uses a Kaplan-Meier curve to contrast Lutathera against a control group, highlighting the clinical limitation of the current standard of care.frame_problem
Open slide detailLoop · Cost Of Inaction
14
The chart compares median progression vs median survival in months across three patient cohorts (Pancreatic, GI, Overall).size_opportunity
Open slide detailLoop · Cost Of Inaction
15
The slide uses a chemical structure comparison to illustrate the similarity in binder/chelator while highlighting the difference in radioisotope.present_solution
Open slide detailBeat · Solution
16
The slide uses a process-oriented layout to show the transition between trial phases.plan_implementation
Open slide detailBeat · SolutionLoop · Hypothesis Test
17
The table specifically highlights that there were zero treatment-related serious adverse events (SAE) and zero discontinuations.analyze_data
Open slide detailBeat · SolutionLoop · Hypothesis Test
18
Waterfall plot displays individual patient responses; benchmarking table compares ORR against historical standards.show_traction
Open slide detailBeat · SolutionLoop · Hypothesis Test
19
The chart tracks patient follow-up in weeks, with markers indicating dose, dose reduction, and clinical response (Partial Response, Progressive Disease, Stable show_traction
Open slide detailBeat · SolutionLoop · Hypothesis Test
20
compare_peers
Open slide detailBeat · SolutionLoop · Hypothesis Test
21
The slide uses a standard clinical trial flow diagram (Population -> Treatment -> Endpoints -> Crossover).plan_implementation
Open slide detailLoop · Hypothesis Test
22
The slide uses a three-column layout to break down the market opportunity into patient population, pricing, and launch dynamics.size_opportunity
Open slide detailBeat · Market Sizing
23
The slide highlights that 47% of SCLC samples show some level of SSTR2 expression, with 27% showing high expression.analyze_data
24
Includes a visual case study with PET scan images showing tumor reduction.show_traction
25
The chart shows tumor growth over 57 days across four treatment groups, with the combination therapy (green line) demonstrating the most effective tumor suppresshow_traction
26
The slide outlines a clinical trial protocol for a combination therapy involving RYZ101, chemotherapy, and PD-L1 inhibitors.plan_implementation
27
Includes PET scan imagery and a pharmacokinetic tumor uptake graph comparing RAYZ-SSTR to DOTATATE.present_solution
28
CMC stands for Chemistry, Manufacturing, and Controls. The slide highlights infrastructure investment and current CDMO reliance.present_solution
29
The workflow includes a feedback loop from in vivo screening back to binder discovery.present_solution
30
The slide uses a staircase-style diagram to represent progression in clinical relevance of data.plan_implementation
31
Includes IHC staining images and a waterfall plot showing tumor shrinkage.present_solution
32
The slide demonstrates the efficacy and specificity of the drug candidate in a preclinical model.present_solution
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Comparison of 225Ac vs 177Lu efficacy at significantly different dose levels.show_traction
34
Includes clinical imaging examples for two patients.show_traction
35
The slide uses a longitudinal imaging sequence to demonstrate drug efficacy/retention.show_traction
36
The slide uses a process flow diagram to illustrate the regulatory and clinical milestones.plan_implementation
37
The slide lists 24 investor logos/names.show_traction
38
plan_implementation
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Includes 88 FTEs count and board member list.other
Open slide detailBeat · Team
40
The slide uses a vertical process flow to illustrate vertical integration.present_solution
41
This is a closing or transition slide featuring the company logo and mission statement.inspire_vision