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Chimerix · pitchdeck

Chimerix | Investor Presentation Deck | 38 slides

38 pages · 5 arc beats · 3 loops

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Chimerix | Investor Presentation Deck | 38 slides

Chimerix · 2023-03
arc beats above · slides in the middle · loops below · scroll → 3 LOOPS
SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
HOVER FOR DETAILS · CLICK A SLIDE FOR FULLSCREEN · STEP 2
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Deck intelligence map

5
coverage by narrative range · generated from this deck JSON
Narrative range 5 total
Metadata
Components
Metrics
Tools
Frameworks
Beats
Loops
Problem (Identify pain) 1 slides 100% 1/1 slides 100% 1/1 slides · 6 hits
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100% 1/1 slides 100% 1/1 slides Agitate (Make it worse) 1 slides 100% 1/1 slides 100% 1/1 slides · 8 hits
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100% 1/1 slides 100% 1/1 slides Solution (Provide relief) 1 slides 100% 1/1 slides 100% 1/1 slides · 5 hits
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100% 1/1 slides 100% 1/1 slides 100% 1/1 slides 100% 1/1 slides Market Size 1 slides 100% 1/1 slides 100% 1/1 slides · 7 hits
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Financials 1 slides 100% 1/1 slides 100% 1/1 slides · 3 hits
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Slide inventory

38
every slide · same image gating as the playbook
01
Slide 1
front_matter
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02
other
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03
summarize
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04
The slide uses a Gantt-style chart to represent drug development stages.plan_implementation
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05
transition
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06
Includes Kaplan-Meier survival curves and a comparative table of natural history vs. ONC201 treatment.frame_problem
Open slide detailBeat · Problem (Identify pain)Loop · Cost Of Inaction
07
Data presented includes ORR, DOR, time to response, disease control rate, PFS, and overall survival metrics.show_traction
Open slide detailBeat · Agitate (Make it worse)Loop · Cost Of Inaction
08
The slide details specific inclusion/exclusion criteria including age, mutation status, disease progression, prior therapy, and washout periods.present_framework
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09
The slide highlights clinical trial results with specific response and disease control rates.show_traction
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10
The chart is a waterfall plot (often called a swimmer plot or waterfall efficacy plot in oncology).show_traction
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11
The chart is a waterfall plot showing efficacy of ONC201 in H3 K27M-mutant Diffuse Midline Glioma.show_traction
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12
The chart is a classic 'spider plot' or 'swimmer plot' variant used in oncology to show individual patient tumor burden trajectories over time.show_traction
Open slide detailBeat · Solution (Provide relief)Loop · Quick Win Big Bet
13
Data presented in two tables comparing integrated safety data from glioma patients and a healthy adult study.analyze_data
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14
The table compares 'All patients' against 'RANO HGG Responders' and 'RANO HGG and/or LGG Responders' across survival and clinical metrics.show_traction
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15
The table uses a color-coded heatmap (green/pink) to indicate positive vs negative characteristics of trial design and outcomes.compare_peers
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16
transition
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17
The slide uses a process flow diagram to illustrate the clinical trial structure.plan_implementation
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18
summarize
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19
The slide details the statistical powering and success thresholds for a clinical trial design.present_framework
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20
The chart shows a dose-response curve where longer incubation times (48+ hours) shift the curve to the left compared to 24 hours, indicating higher potency/effipresent_solution
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21
transition
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22
size_opportunity
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23
Waterfall plot shows 10 patients; 8 show reduction in tumor burden.show_traction
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24
Includes a BioRender diagram illustrating the molecular pathway.present_solution
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25
The slide uses a combination of molecular mechanism diagrams, bar charts, PET scans, and dot plots to explain the biological rationale for a drug's efficacy.analyze_data
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26
transition
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27
Includes molecular structure of ONC206 and protein structures of targets DRD2 and ClpP.present_solution
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28
Includes citations for specific cancer models and experimental data.show_traction
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29
The slide uses in vitro cell viability data and PK modeling to justify a dose intensification strategy.present_solution
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30
Includes logos for NIH and Pacific Pediatric Neuro-Oncology Consortium.show_traction
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31
Includes footnote references for data sources and royalty obligations.size_opportunity
Open slide detailBeat · Market Size
32
transition
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33
The slide shows a bioluminescence imaging comparison of tumor burden in mice treated with Vehicle, ONC201, and ONC212.present_solution
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34
The chart shows a clear dose-response/time-response relationship for viral load reduction.show_traction
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35
transition
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36
summarize
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37
The slide uses a process-flow diagram to link financial strength to clinical milestones.argue_timing
Open slide detailBeat · FinancialsLoop · Why Now
38
front_matter
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