AstraZeneca | Investor Event Presentation Deck | 42 slides

AstraZeneca · 2022-12
arc beats above · slides in the middle · loops below · scroll → 4 LOOPS
SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
HOVER FOR DETAILS · CLICK A SLIDE FOR FULLSCREEN · STEP 2
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6
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Slide inventory

42
every slide · same image gating as the playbook
01
Slide 1
front_matter
Open slide detailBeat · Setup
02
other
Open slide detailBeat · Setup
03
introduce_nominees
Open slide detailBeat · Setup
04
front_matter
Open slide detailBeat · Setup
05
introduce_nominees
Open slide detailBeat · Setup
06
Includes a footer with acronym definitions.summarize
Open slide detailBeat · Complication
07
The slide uses a four-column layout to segment strategic focus areas (HER2-high, HR+, gBRCA, TNBC).summarize
Open slide detailBeat · Complication
08
The slide uses a timeline framework to establish credibility and future-looking innovation.present_solution
Open slide detailBeat · Complication
09
The slide uses a horizontal timeline/process flow to map patient treatment stages against therapeutic interventions and resistance mechanisms.plan_implementation
Open slide detailBeat · Complication
10
front_matter
Open slide detailBeat · Problem & ComplicationLoop · Quick Win Big Bet
11
The slide uses a process flow diagram to illustrate the randomization of patients into treatment arms.establish_context
Open slide detailBeat · Problem & ComplicationLoop · Quick Win Big Bet
12
Includes a table of patients at risk below the x-axis and a summary table of PFS events, median PFS, and hazard ratio.analyze_data
Open slide detailBeat · Problem & ComplicationLoop · Quick Win Big Bet
13
Includes a table of PFS events, median PFS, and adjusted hazard ratio (HR) alongside the survival plot and risk table.analyze_data
Open slide detailBeat · Problem & ComplicationLoop · Quick Win Big Bet
14
Includes a risk table and summary statistics table (Median PFS, HR).analyze_data
Open slide detailBeat · Problem & ComplicationLoop · Quick Win Big Bet
15
Includes risk tables and hazard ratios (HR) with 95% confidence intervals.analyze_data
Open slide detailBeat · Problem & ComplicationLoop · Quick Win Big Bet
16
Includes a forest plot for subgroup analysis and a summary table for prior treatments.analyze_data
Open slide detailBeat · Problem & ComplicationLoop · Quick Win Big Bet
17
The slide uses a mirrored bar chart to compare adverse event frequencies by grade, alongside a summary table of clinical safety outcomes.analyze_data
Open slide detailBeat · Problem & ComplicationLoop · Quick Win Big Bet
18
summarize
Open slide detailBeat · Problem & ComplicationLoop · Quick Win Big Bet
19
Includes corporate branding, speaker name/title, and scientific imagery.front_matter
Open slide detailBeat · Evidence & Proof
20
The diagram illustrates a randomized clinical trial flow.present_framework
Open slide detailBeat · Evidence & Proof
21
The slide presents clinical trial baseline data, likely for a breast cancer study given the markers (ER+, PgR+, ESR1m, CDK4/6i).analyze_data
Open slide detailBeat · Evidence & Proof
22
The slide uses a standard Kaplan-Meier survival analysis framework common in oncology clinical trials.analyze_data
Open slide detailBeat · Evidence & ProofLoop · Before After
23
Clinical trial data visualization showing hazard ratios and median PFS.analyze_data
Open slide detailBeat · Evidence & ProofLoop · Before After
24
Clinical trial data visualization showing progression-free survival (PFS) curves with associated hazard ratios and event counts.analyze_data
Open slide detailBeat · Evidence & ProofLoop · Before After
25
The slide uses a split-panel design to compare two patient cohorts (ESR1m detectable vs not detectable).analyze_data
Open slide detailBeat · Evidence & ProofLoop · Before After
26
Clinical trial data visualization showing hazard ratios and median PFS.analyze_data
Open slide detailBeat · Evidence & Proof
27
The table compares adverse event (AE) frequencies, treatment-related AEs (TRAEs), and dose modifications.analyze_data
Open slide detailBeat · Evidence & Proof
28
The table lists 15 specific adverse events plus 'Any AE' across 4 cohorts, with two columns per cohort (All grades, Grade >=3).analyze_data
Open slide detailBeat · Evidence & Proof
29
The slide summarizes the primary outcomes of the SERENA-2 trial, confirming PFS benefits and safety, and mentions ongoing Phase III trials (SERENA-4 and SERENA-summarize
Open slide detailBeat · Evidence & Proof
30
SABCS stands for San Antonio Breast Cancer Symposium.transition
Open slide detailBeat · Impact & Next Steps
31
Includes Kaplan-Meier survival curve and key efficacy metrics.analyze_data
Open slide detailBeat · Impact & Next Steps
32
Includes a waterfall plot for the BEGONIA trial.summarize
Open slide detailBeat · Impact & Next Steps
33
front_matter
Open slide detailBeat · Impact & Next Steps
34
The slide uses a visual layout with three circular metrics to emphasize the scale of the problem.frame_problem
Open slide detailBeat · Impact & Next StepsLoop · Confession
35
The slide uses a patient journey/treatment pathway framework to map current standard of care against emerging therapeutic interventions.present_solution
Open slide detailBeat · Impact & Next StepsLoop · Confession
36
Uses a before-after-bridge structure to frame the problem (poor outcomes) and the solution (Capivasertib).diagnose_problem
Open slide detailBeat · Impact & Next StepsLoop · Confession
37
The slide uses a stacked bar chart to show market share evolution over three quarters and bulleted lists to summarize clinical trial outcomes.analyze_data
Open slide detailBeat · Impact & Next Steps
38
state_next_steps
Open slide detailBeat · Action
39
introduce_nominees
Open slide detailBeat · Action
40
appendix
Open slide detailBeat · Action
41
Clinical trial baseline characteristics table.analyze_data
Open slide detailBeat · Action
42
other
Open slide detailBeat · Action