Larimar Therapeutics | Investor Presentation Deck | 32 slides

Larimar Therapeutics · 2022-10
arc beats above · slides in the middle · loops below · scroll → 3 LOOPS
SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
HOVER FOR DETAILS · CLICK A SLIDE FOR FULLSCREEN · STEP 2
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Slide inventory

32
every slide · same image gating as the playbook
01
Slide 1
front_matter
03
summarize
Open slide detailBeat · Executive Summary
04
The slide uses a timeline framework to demonstrate the longevity of IP protection.present_framework
05
The slide uses a medical context to establish the urgency and market need for a new therapy.frame_problem
Open slide detailBeat · ProblemLoop · Cost Of Inaction
06
The slide uses a comparison frame to illustrate the mechanism of action for the drug candidate.present_solution
Open slide detailBeat · SolutionLoop · Quick Win Big Bet
07
The slide outlines a 28-day treatment period with daily administration, targeting Friedreich's ataxia patients.plan_implementation
Open slide detailBeat · Roadmap
08
FA likely refers to Friedreich's Ataxia; FXN refers to frataxin protein.show_traction
Open slide detailBeat · TractionLoop · Hypothesis Test
09
The slide uses a process flow diagram to show the relationship between SAD and MAD trials.present_framework
Open slide detailBeat · TractionLoop · Hypothesis Test
10
The slide details the dosing schedule (13 days) and specific sampling days for buccal cells, skin, and platelets across three cohorts with different dosages.analyze_data
Open slide detailBeat · TractionLoop · Hypothesis Test
11
The slide displays two dot plots with error bars representing median and 25th/75th percentiles for different dose cohorts over time.show_traction
Open slide detailBeat · TractionLoop · Hypothesis Test
12
The chart displays a longitudinal study of FXN concentration across different dose groups (Placebo, 25mg, 50mg, 100mg) at Baseline, Day 4/7, and Day 13.show_traction
Open slide detailBeat · TractionLoop · Hypothesis Test
13
The slide uses a two-part structure to address clinical safety and non-clinical toxicology findings.show_traction
Open slide detailBeat · TractionLoop · Hypothesis Test
14
The slide uses a horizontal layout with four distinct trial descriptions, each paired with an icon.plan_implementation
15
The slide uses a simple three-row layout to summarize the drug's purpose, current data status, and future milestones.summarize
16
summarize
17
state_next_steps
19
Standard clinical trial demographic table.analyze_data
20
Clinical trial data table showing age at onset, age at diagnosis, and assistive device usage.analyze_data
21
The slide displays two dot plots with error bars representing median and 25th/75th percentiles.show_traction
22
The slide presents two dot plots with error bars representing median and 25th/75th percentiles for FXN concentration and change from baseline.show_traction
23
analyze_data
24
The slide uses a standard corporate team bio layout with 10 members arranged in two rows of five.other
25
The slide serves as a credibility-building asset by showcasing alignment with a key patient advocacy group.establish_context
26
The slide presents the Scientific Advisory Board members with headshots and brief professional biographies.other
27
The slide uses a two-column list format to contrast cardiac and neurologic study outcomes.show_traction
28
Kaplan-Meier survival curve showing significant separation between treatment and vehicle groups.show_traction
29
The slide uses a bulleted list with checkmarks to summarize key findings from a specific mouse model study.show_traction
30
Data shows functional replacement of hFXN and normalization of gene expression.show_traction
31
Data presented as line charts with error bars, comparing KO: CTI-1601, KO: Vehicle, and Wild-type: Vehicle.show_traction
32
Data presented as line charts showing percent change over time (weeks 4 and 8) for Ejection Function and Fractional Shortening.show_traction