Aravive | Investor Presentation Deck | 39 slides

Aravive · 2022-09
arc beats above · slides in the middle · loops below · scroll → 2 LOOPS
SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
HOVER FOR DETAILS · CLICK A SLIDE FOR FULLSCREEN · STEP 2
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Slide inventory

39
every slide · same image gating as the playbook
01
Slide 1
Includes company logo, ticker symbol, and a representative photo of a patient.front_matter
03
present_solution
04
The slide uses academic citations to establish the clinical relevance of the target protein.frame_problem
Open slide detailBeat · Problem (Identify pain)Loop · Cost Of Inaction
05
Includes a scientific diagram of the signaling pathway and references to academic literature.frame_problem
Open slide detailBeat · Problem (Identify pain)Loop · Cost Of Inaction
06
Includes a bifurcation diagram illustrating the relationship between SNAIL and ZEB mRNA levels in different cell phenotypes.frame_problem
Open slide detailBeat · Problem (Identify pain)Loop · Cost Of Inaction
07
The slide uses a visual comparison of biological mechanisms to argue for the superiority of the company's 'Decoy AXL Receptor' approach.compare_peers
Open slide detailBeat · Agitate (Make it worse)
08
The slide uses a two-column layout to contrast the drug's engineering/profile with its biomarker/IP strategy.present_solution
Open slide detailBeat · Agitate (Make it worse)
09
The slide uses a standard organizational structure layout with headshots and a logo grid for credibility.other
Open slide detailBeat · Solution (Provide relief)
10
The slide uses a horizontal bar chart format to represent clinical trial stages for different drug combinations.plan_implementation
Open slide detailBeat · Solution (Provide relief)
11
The pie chart visualizes the relative size of the patient populations described in the list.size_opportunity
Open slide detailBeat · Solution (Provide relief)
12
front_matter
Open slide detailLoop · Quick Win Big Bet
13
The slide uses a process flow diagram to show the Phase 1b study arms.show_traction
Open slide detailLoop · Quick Win Big Bet
14
Includes specific clinical metrics (ORR, mPFS, mOS) comparing patients above and below the Minimal Efficacious Concentration (MEC).analyze_data
Open slide detailLoop · Quick Win Big Bet
15
The slide includes two scatter plots with error bars and two summary tables of experimental data.analyze_data
Open slide detailLoop · Quick Win Big Bet
16
The slide uses a swimmer plot (left) and a waterfall plot (right) to visualize clinical response.show_traction
17
The slide highlights clinical efficacy data from a Phase 1b trial (PROC).show_traction
18
The slide compares clinical outcomes (ORR, SD, CBR, PD) across four cohorts: two treatment groups and two historical control groups.compare_peers
19
Includes trial design diagram with randomization and endpoint hierarchy.plan_implementation
20
The slide uses qualitative feedback from healthcare providers and KOLs to validate market demand.show_traction
21
front_matter
22
The slide uses a process flow diagram to illustrate the trial structure.present_framework
23
The slide includes detailed footnotes explaining specific adverse events and patient outcomes.analyze_data
24
Includes footnotes comparing results to historical METEOR and CANTATA studies.show_traction
25
Data compares low vs high biomarker groups across different dosage cohorts.analyze_data
26
The slide outlines a clinical trial protocol including randomization, interim analysis for accelerated approval, and primary/secondary endpoints.plan_implementation
27
The slide uses a table to summarize key value propositions and speech bubbles to provide direct KOL validation.illustrate_case
28
The slide features a photo of a patient being comforted, emphasizing the human element of the medical treatment.front_matter
29
The slide outlines a standard clinical trial schema with a dose-finding/safety phase followed by a randomized efficacy phase.plan_implementation
30
Data cutoff date is August 18, 2022. N=21 patients.analyze_data
31
Includes a footnote comparing results to a historical P3 study.show_traction
32
Swimmer plot showing patient IDs on y-axis and weeks on study on x-axis, with various clinical status markers.analyze_data
33
Data shows a clear correlation between achieving MEC and better clinical outcomes in PDAC patients.analyze_data
34
PDAC stands for Pancreatic Ductal Adenocarcinoma. RP2D stands for Recommended Phase 2 Dose.plan_implementation
35
Includes qualitative feedback from KOLs and healthcare providers regarding clinical utility and patient selection.argue_timing
36
The slide uses a horizontal timeline with four distinct time periods, each containing multiple clinical trial or regulatory events.plan_implementation
37
Data as of 6/30/2022.summarize
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summarize
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front_matter