Caribou Biosciences | IPO Presentation Deck | 44 slides

Caribou Biosciences · 2021-07
arc beats above · slides in the middle · loops below · scroll → 3 LOOPS
SETUP TENSION ANALYSIS EVIDENCE RESOLUTION APPENDIX
HOVER FOR DETAILS · CLICK A SLIDE FOR FULLSCREEN · STEP 2
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Slide inventory

44
every slide · same image gating as the playbook
01
Slide 1
Includes date (July 2021) and company tagline.front_matter
03
summarize
04
The slide is divided into two sections: a 2x2 grid for executive bios and a logo grid for investors.other
05
transition
06
The slide uses a structured list format to highlight four key pillars of the company's value proposition.summarize
07
The slide uses a structured grid layout to categorize the company's technology platform and pipeline.present_solution
Open slide detailBeat · SolutionLoop · Golden Circle
08
The slide uses a visual comparison framework to contrast traditional autologous therapy with the company's allogeneic focus.compare_peers
Open slide detailBeat · SolutionLoop · Golden Circle
09
Uses a before-after-bridge style logic to frame the problem (efficacy challenge) and the company's solution (persistence).frame_problem
Open slide detailBeat · ProblemLoop · Golden Circle
10
The chart uses a conceptual line graph to show the impact of two specific genetic modifications on the duration of CAR-T cell activity.present_solution
Open slide detailBeat · SolutionLoop · Golden Circle
11
The slide uses a standard pharmaceutical pipeline visualization format.plan_implementation
Open slide detailBeat · SolutionLoop · Golden Circle
12
The slide serves as a section divider or introduction to the technology stack.present_solution
Open slide detailBeat · SolutionLoop · Golden Circle
13
present_solution
Open slide detailBeat · SolutionLoop · Golden Circle
14
The slide uses a process flow diagram to show the transition from raw materials to patient treatment.present_solution
Open slide detailBeat · SolutionLoop · Golden Circle
15
The charts show that chRDNA guides maintain high on-target editing while significantly reducing off-target editing compared to all-RNA guides.show_traction
Open slide detailBeat · TractionLoop · Zoom In
16
present_solution
Open slide detailBeat · TractionLoop · Zoom In
17
The chart is a flow cytometry plot showing insertion efficiency across two inserts.present_solution
Open slide detailBeat · TractionLoop · Zoom In
18
The slide uses a before/after diagram to explain the biological problem of translocation and a comparative box to show the performance improvement.present_solution
Open slide detailBeat · TractionLoop · Zoom In
19
transition
Open slide detailBeat · Traction
20
The slide uses a comparison table to demonstrate the competitive advantages of CB-010's specific gene-editing features.compare_peers
Open slide detailBeat · Traction
21
Uses a before-after comparison framework to explain the mechanism of action.present_solution
Open slide detailBeat · Traction
22
Includes bioluminescence imaging time-series and Kaplan-Meier survival curve.show_traction
Open slide detailBeat · Traction
23
Kaplan-Meier survival plots are standard for preclinical efficacy demonstration.show_traction
Open slide detailBeat · Traction
24
The slide outlines a standard 3+3 dose escalation clinical trial design.plan_implementation
Open slide detailBeat · Traction
25
The slide details the transition from healthy donor leukapheresis through genetic modification (using AAV, Cas9, and chRDNA) to final cryopreservation and treatpresent_solution
Open slide detailBeat · Traction
26
present_solution
Open slide detailBeat · Traction
27
The slide features a stylized microscopic image of cells, likely T-cells, as a background.transition
Open slide detailBeat · Traction
28
The slide uses a checkmark/cross comparison table to demonstrate competitive advantage.compare_peers
Open slide detailBeat · Traction
29
The slide uses a biological process diagram to illustrate the 'cloaking' mechanism.present_solution
Open slide detailBeat · Traction
30
The chart shows in vitro cytotoxicity measured 24 hours after co-incubation at various effector-to-target ratios.present_solution
Open slide detailBeat · Traction
31
Kaplan-Meier survival curves showing superior efficacy of CB-011.show_traction
Open slide detailBeat · Traction
32
present_solution
Open slide detailBeat · Traction
33
transition
Open slide detailBeat · Traction
34
The slide uses a checkmark vs X comparison table to establish competitive advantage.compare_peers
Open slide detailBeat · Traction
35
The chart is a Kaplan-Meier survival plot. The p-value < 0.0001 indicates statistical significance.show_traction
Open slide detailBeat · Traction
36
present_solution
Open slide detailBeat · Traction
37
The slide features a stylized illustration of a cell, likely an NK cell, interacting with other cells.transition
38
The diagram shows a multi-step biological process: Gene editing, two stages of differentiation, and expansion.present_solution
39
The slide presents four distinct assays validating the functional equivalence of iNK cells to primary NK cells.show_traction
40
present_solution
41
transition
42
The slide uses a split-column layout to contrast past performance with future roadmap items.show_traction
43
The slide uses a structured list format to highlight four key pillars of the company's value proposition.present_solution
44
state_next_steps