Inspire Medical Systems, Inc. (INSP)

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Market Segmentation Pyramid slide · 70%

Prevalence & Economic Costs: Sleep apnea affects +100 million people worldwide; 17 million in U.S. with moderate to severe OSA; ~2 million prescribed CPAP; $65-$165 billion economic cost.

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Top-down funnel calculation from total population to addressable market value.

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The slide includes a critical annotation highlighting that the core assumption (2 million patients) is based on 'Company estimates'.