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  "documentTitle": "MaxCyte | IPO Presentation Deck | 34 slides",
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  "authorName": "MaxCyte",
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  "presentationDate": "2021-07-01 00:00:00",
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  "notes": "The slide uses a 4-step process diagram to illustrate the mechanism of action for electroporation.",
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      "text": "Electrical pulses are applied to cells suspended between two electrodes, which creates an electric field and polarization of the membrane. At a certain electrical field threshold, openings form in the cellular membrane (can be simplistically thought of as pores). The size and distribution of these openings depends on the intensity of the applied electric field and duration of cell exposure. The openings allow the entry of macromolecules such as RNA, DNA or proteins (such as Cas9/guide RNA complexes) through the cell membrane. A key discovery in EP was that the e effects of electroporation on the cellular membrane are reversible. Once the electric field is removed, the membrane has the capacity to reseal, trapping the molecules that passed across the membrane within the cytoplasm.",
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      "kind": "title",
      "text": "What is Electroporation?",
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