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  "notes": "Focuses on regulatory strategy and clinical trial progression for EBO-301.",
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      "text": "Microbial complexity in TR-MAC patient population makes sputum culture conversion difficult if not impossible to achieve; not required for approval based on FDA Guidance",
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      "text": "Elevating QOL-b respiratory domain, change from baseline to month 6 as the primary endpoint\nSubmitted statistical analysis plan to FDA (1Q25)\nGoal to Unblind 97 Patients enrolled in truncated Phase 3 (2Q25, subject to timing and outcome of any FDA response to SAP submission) ahead of potential FDA meeting\nMeet with FDA to review Phase 2 and Phase 3 data and align on path forward",
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      "text": "Next: Unblind Phase 3 Data",
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