{
  "docId": "019de077-2e43-774b-aad6-58a03a29d59d",
  "docSlug": "207557819f8810b573d3e2a3179a9bac",
  "documentTitle": "AstraZeneca | Investor Event Presentation Deck | 55 slides",
  "authorId": "astrazeneca",
  "authorName": "AstraZeneca",
  "documentKindSlug": "conference-presentation",
  "documentKindLabel": "Conference presentation",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2024-09-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 15,
  "pageCount": 55,
  "prevPage": 14,
  "nextPage": 16,
  "slideType": "comparison_table",
  "function": "compare_peers",
  "density": "dense",
  "nDataPoints": 0,
  "notes": "The slide uses a checkmark/cross comparison matrix to demonstrate the superiority of QCS over IHC.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de077-2e43-774b-aad6-58a03a29d59d/15",
  "deckHref": "/decks/019de077-2e43-774b-aad6-58a03a29d59d",
  "deckJsonHref": "/decks/019de077-2e43-774b-aad6-58a03a29d59d.json",
  "deckAnchorHref": "/decks/019de077-2e43-774b-aad6-58a03a29d59d#slide-15",
  "components": [
    {
      "bbox": {
        "h": 0.06,
        "w": 0.75,
        "x": 0.04,
        "y": 0.93
      },
      "kind": "disclaimer",
      "text": "Data cutoff: March 1, 2024. 1. Based on the number of patients in the respective actionable genomic alteration subsets. Values were calculated based on patient data in the electronic case report forms. 1. Sands J et al. Abstract #OA08.03 presented at the 2024 World Conference on Lung Cancer. 2. Ahn M-J, et al. Abstract 509MO presented at the European Society of Medical Oncology. Collaboration partner: Daiichi Sankyo (Dato-DXd).",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "6bb6f0d6-57e9-4cd5-b2e8-7da927985cd8",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.5,
        "w": 0.4,
        "x": 0.04,
        "y": 0.33
      },
      "kind": "list",
      "text": "TROP2 is highly expressed across tumour and normal tissue; TROP2 has variable patterns of expression in membrane and cytoplasm; Total TROP2 IHC does not reflect subset of TROP2 to which Dato-DXd binds/internalises",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "ff61d69c-9e99-4823-bf50-64bec4b3da02",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.65,
        "w": 0.52,
        "x": 0.44,
        "y": 0.25
      },
      "kind": "table",
      "text": "Comparison matrix of QCS vs IHC across 6 clinical/biological criteria",
      "attrs": null,
      "subkind": "data",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "47b67e28-6cf8-4759-ae1c-e5ef5ba4377b",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.06,
        "w": 0.6,
        "x": 0.04,
        "y": 0.05
      },
      "kind": "title",
      "text": "Novel biomarker solution – QCS-NMR for Dato-DXd",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "6f8ba594-d76e-4854-af80-c801dce30306",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.04,
        "w": 0.6,
        "x": 0.04,
        "y": 0.12
      },
      "kind": "title",
      "text": "QCS measures features linked to biological effect unlike conventional IHC",
      "attrs": null,
      "subkind": "subtitle",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "0ddb0218-2d05-40fe-b33f-af933805f067",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "2x2 matrix",
      "slug": "matrix-2x2",
      "agent": null,
      "layer": "slide",
      "matchId": "ea8242a0-f9bf-43d8-bc84-1ea1864a7cdd",
      "evidence": "table/data: Comparison matrix of QCS vs IHC across 6 clinical/biological criteria",
      "confidence": 0.7
    }
  ],
  "frameworks": [
    {
      "name": "comparison_frame",
      "slug": null,
      "matchId": "052fa79a-460a-460e-9020-70df4259f19f",
      "evidence": "Direct comparison of two methodologies (QCS vs IHC) across multiple criteria.",
      "confidence": 0.9
    }
  ],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}