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  "documentTitle": "Nuvalent | Investor Presentation Deck | 42 slides",
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  "presentationDate": "2024-04-01 00:00:00",
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  "notes": "The slide highlights the Recommended Phase 2 Dose (RP2D) selection based on safety and PK data.",
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      "text": "Preliminary pharmacokinetic profile (Presented October 2022)",
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      "text": "Data as of 13 Sep 2022, for patients treated by 01 Sep 2022. Pharmacokinetic data for 125 mg QD cohort are not shown due to immaturity.",
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      "text": "MTD was not reached; No clinically significant exposure-response relationships; Wide therapeutic window; 100 mg daily maintained steady state plasma levels above all target efficacy thresholds",
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      "text": "RP2D of 100mg QD Met All Desired Clinical Characteristics",
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