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  "notes": "The slide uses a hub-and-spoke diagram to illustrate the interaction of LSD1 with various protein complexes, receptors, and RNAs.",
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      "text": "LSD1 is not only an epigenetic modifier but also forms a variety of complexes with transcription factors, promoters, activators, corepressors and non-coding RNAs. This variety of functions can drive tumourigenesis and modify the tumour microenvironment to enable enhanced cancer cell proliferation. LSD1 is overexpressed in many cancer types across haematological and solid tumours and correlates with poor patient survival. Literature has shown potential benefit of LSD1 inhibition in indications including AML, and neuroendocrine-like cancer types including SCLC, pancreatic and prostate cancer.",
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      "text": "Graphic adapted from Ismail et al. Epigenetics Chromatin, 2018. 1) Kim et al. J Biomed Sci, 2021; 2) Maes et al. Cancer Cell, 2018; 3) Mohammad et al. Cancer Cell, 2015; 4) Qin et al. Cancer Lett, 2014; 5) Kumaraswamy et al. JCI Insight, 2023.",
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      "text": "LSD1 inhibition leads to differentiation of tumour cells",
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