{
  "docId": "019de077-0326-7579-845c-ff13347b3147",
  "docSlug": "a6759fd47798a8f3f6e744ad8917865e",
  "documentTitle": "Exscientia | Investor Presentation Deck | 93 slides",
  "authorId": "exscientia",
  "authorName": "Exscientia",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2024-03-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 29,
  "pageCount": 93,
  "prevPage": 28,
  "nextPage": 30,
  "slideType": "solution",
  "function": "present_solution",
  "density": "dense",
  "nDataPoints": 0,
  "notes": "MD stands for Molecular Dynamics. The slide features a 3D protein-ligand binding visualization.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de077-0326-7579-845c-ff13347b3147/29",
  "deckHref": "/decks/019de077-0326-7579-845c-ff13347b3147",
  "deckJsonHref": "/decks/019de077-0326-7579-845c-ff13347b3147.json",
  "deckAnchorHref": "/decks/019de077-0326-7579-845c-ff13347b3147#slide-29",
  "components": [
    {
      "bbox": {
        "h": 0.6,
        "w": 0.45,
        "x": 0.5,
        "y": 0.24
      },
      "kind": "image",
      "text": "3D protein-ligand binding visualization",
      "attrs": null,
      "subkind": "illustration",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "a5297b14-65e4-41fb-b552-09a249ab0e75",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.4,
        "x": 0.5,
        "y": 0.8
      },
      "kind": "legend",
      "text": "Donor (blue), Acceptor (red), Apolar (yellow)",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "448f8664-4dcd-4654-b0da-3bad848867c9",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.15,
        "w": 0.35,
        "x": 0.14,
        "y": 0.68
      },
      "kind": "list",
      "text": "Automation and accuracy: Developing novel methods to enhance sampling (e.g., Monte Carlo water sampling and 3D edge mapping) along with absolute free energy method",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "0d13cbf4-6878-4bb4-ae63-6bf275f4632b",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.35,
        "x": 0.14,
        "y": 0.53
      },
      "kind": "list",
      "text": "Potency prediction: Relative and absolute binding energy prediction – physics-based methods",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "521818cb-8bc0-4ee6-8763-3d8b2b08c8c5",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.35,
        "x": 0.14,
        "y": 0.38
      },
      "kind": "list",
      "text": "Pose prediction: Metadynamics simulations can accurately determine real binding pose from possibilities from our algorithms",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "d54fb2fa-8798-4eac-b49d-11462d02c49b",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.07,
        "w": 0.45,
        "x": 0.03,
        "y": 0.25
      },
      "kind": "paragraph",
      "text": "MD methods actively used to provide improved precision pose and potency prediction",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "f05e636c-9865-4ade-a732-511a24f0c68a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.04,
        "w": 0.55,
        "x": 0.07,
        "y": 0.13
      },
      "kind": "title",
      "text": "Automated MD toolkit actively applied on discovery projects",
      "attrs": null,
      "subkind": "action-title",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "92d6fd88-c7bd-4c17-86ed-b5b5faca443a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.4,
        "x": 0.07,
        "y": 0.06
      },
      "kind": "title",
      "text": "Automated and scalable MD toolbox",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "2c7e1651-4640-45d6-9b00-338b9b94f020",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "List presentation",
      "slug": "list-presentation",
      "agent": null,
      "layer": "slide",
      "matchId": "06a3717f-6f26-420d-a326-0eb945aaf99e",
      "evidence": "list/bullet: Automation and accuracy: ... list/bullet: Pose prediction: ...",
      "confidence": 0.8
    }
  ],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 40,
      "from": 25,
      "beatId": "d92385d8-1c07-440d-b566-4554803a9637",
      "arcName": "The Sparkline",
      "arcSlug": "sparkline",
      "beatName": "Solution (Provide relief)",
      "beatSlug": "problem-agitate-solution-solution-provide-relief",
      "evidence": "Presentation of Exscientia's AI-driven solution and its applications",
      "position": 2,
      "confidence": 0.8,
      "parentBeatName": "Resolution",
      "parentBeatSlug": "resolution"
    }
  ],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}