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  "documentTitle": "Nuvectis Pharma | Investor Presentation Deck | 25 slides",
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  "authorName": "Nuvectis Pharma",
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  "presentationDate": "2024-01-01 00:00:00",
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  "notes": "Includes a biological pathway diagram and an IC50 dose-response curve.",
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      "text": "NXP900 - IC50 for YAP1 nuclear localization: 24.3nM",
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      "text": "Genetic alterations in the hippo pathway (FAT1-4, YAP1, TAZ) are highly prevalent in cancers of squamous cell origin and confer sensitivity to NXP900. YES1 drives tumor growth via phosphorylation and nuclear localization of YAP1. Significant unmet medical need opportunities within the squamous cancer universe -> Regulatory opportunity",
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      "text": "Targeting YES1 in Cancers of Squamous Cell Origin",
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      "evidence": "NXP800 Potential Opportunity in Multiple Cancers and NXP900 Potential Market Opportunity",
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