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  "notes": "Data cut-off: 8 Aug 2023. N=93 patients.",
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      "text": "Data cut-off: 8 Aug 2023. Abbreviations: ALT, AST, CPK, DLT, TRAE. Footnotes regarding specific patient outcomes and source.",
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      "text": "MTD has not been identified; 1 DLT: transient asymptomatic Grade 4 CPK increase. Infrequent TRAEs requiring dose modification: 2% discontinued, 5% dose-reduced. Preliminary overall safety profile consistent with avoiding TRK-related neurotoxicities.",
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      "text": "Treatment-Related Adverse Events (TRAEs) in ≥ 5% of patients. All Treated Patients (N = 93). Columns: Grade 1, Grade 2, Grade ≥3, Any Grade. Rows: Any TRAE, ALT increased, AST increased, Nausea, Dysgeusia, Constipation, Fatigue, Peripheral edema.",
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      "text": "Preliminary Safety Profile: Favorable and Consistent with ALK-Selective, TRK-Sparing Design of NVL-655",
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