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  "documentTitle": "Nuvalent | Investor Presentation Deck | 42 slides",
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  "presentationDate": "2024-01-01 00:00:00",
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  "notes": "Data cut-off: 8 Aug 2023. Includes detailed breakdown of response by mutation type and prior treatment history.",
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      "text": "Data cut-off: 8 Aug 2023. Response-evaluable patients with ALK+ NSCLC. 1G, 1st generation ALK TKI (crizotinib); 2G, 2nd generation ALK TKI (alectinib, brigatinib, or ceritinib); CNS, central nervous system; NE, not evaluable; ORR, objective response rate; PD, progressive disease, PR, partial response, RECIST 1.1, Response Evaluation Criteria in Solid Tumours version 1.1; SD, stable disease, TKI, tyrosine kinase inhibitor.",
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      "text": "Source: Lin J.J. et al., AACR-NCI-EORTC 2023.",
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      "text": "Table showing ORR and response counts (PR, SD, PD, NE) across patient cohorts including All NSCLC, CNS Metastases, ALK resistance mutations, and prior TKI treatment.",
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      "kind": "title",
      "text": "Preliminary Activity: Tumor Response Across Heavily Pretreated Patient Populations",
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