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  "documentTitle": "BioAtla | Investor Presentation Deck | 55 slides",
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      "text": "EpCAM expressed on normal epithelial cells and overexpressed in a wide range of tumors (adenocarcinoma). CD3-bispecifics have demonstrated beneficial effects but hampered by dose-limiting toxicity, namely, cytokine release syndrome (CRS)",
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      "text": "BA3182 exhibits efficient tumor shrinkage with superior safety profile. In non-GLP and GLP tox studies in NHP, dual selection results in high selectivity. 160-fold TI increase. MTD not reached. No Cytokine release observed.",
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      "text": "MiXeno Model with HCT116 = Colorectal Cancer Cell Line; 1mg/kg twice/week in mice; Single Dose - non-GLP Toxicity Study; QW x 4 weeks - GLP Toxicity Study",
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      "text": "Safety Profile comparison between WT-EpCAM x WT-CD3 and CAB-EpCAM x CAB-CD3 (BA3182)",
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