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  "documentTitle": "ATAI | Investor Presentation Deck | 34 slides",
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  "authorName": "atai Life Sciences",
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  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2024-01-01 00:00:00",
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  "pageNumber": 12,
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  "notes": "The slide cites a third-party study (Palhano-Fontes et al.) as proxy evidence for DMT efficacy.",
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  "slideHref": "/slides/019de076-928b-754c-8bda-49c7fed3154d/12",
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      "kind": "chart",
      "text": "MADRS Score over time for N, N-DMT vs Placebo",
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      "text": "1. Summary: A single administration of .36 mg/kg met both primary and key secondary efficacy endpoints... 2. Primary endpoint (HAM-D - not shown)... 3. Key secondary endpoint (MADRS - see left)... 4. There were no serious adverse events reported.",
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      "text": "Double-blind, randomized placebo-controlled trial with DMT in 29 patients with treatment-resistant-depression",
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      "text": "Note: TRD = Treatment Resistant Depression; DMT = N,N-Dimethyltryptamine 1. Palhano-Fontes et al. “Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression”, Psychol Med (2019)",
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      "text": "Clinical Evidence: Efficacy in Randomized Control Trial of DMT in TRD",
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