{
  "docId": "019de076-906b-74a9-92f8-5c2872231d60",
  "docSlug": "a8776e7183e96a109d1a49143fc2ff88",
  "documentTitle": "Arbutus Biopharma | Investor Presentation Deck | 26 slides",
  "authorId": "arbutus-biopharma",
  "authorName": "Arbutus Biopharma",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2024-01-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 7,
  "pageCount": 26,
  "prevPage": 6,
  "nextPage": 8,
  "slideType": "problem_statement",
  "function": "frame_problem",
  "density": "overcrowded",
  "nDataPoints": 8,
  "notes": "The slide uses a map to show regional prevalence and a nested circle diagram to show the funnel from total infected to treated patients.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de076-906b-74a9-92f8-5c2872231d60/7",
  "deckHref": "/decks/019de076-906b-74a9-92f8-5c2872231d60",
  "deckJsonHref": "/decks/019de076-906b-74a9-92f8-5c2872231d60.json",
  "deckAnchorHref": "/decks/019de076-906b-74a9-92f8-5c2872231d60#slide-7",
  "components": [
    {
      "bbox": {
        "h": 0.75,
        "w": 0.25,
        "x": 0.75,
        "y": 0.15
      },
      "kind": "chart",
      "text": "Nested circles showing 290M infected, 30M diagnosed, 6.6M treated",
      "attrs": null,
      "subkind": "bubble",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "a3f50181-97f6-4672-8006-4b264d522f8e",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.6,
        "w": 0.55,
        "x": 0.05,
        "y": 0.2
      },
      "kind": "image",
      "text": "World map showing HBV prevalence by region",
      "attrs": null,
      "subkind": "map",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "0751e0d7-d341-4cbb-ba7b-6171ba390882",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.15,
        "x": 0.05,
        "y": 0.15
      },
      "kind": "list",
      "text": ">290M people are chronically infected with HBV, globally.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "24e0c453-4d41-493a-bc9b-f5e99c33987e",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.15,
        "w": 0.15,
        "x": 0.05,
        "y": 0.65
      },
      "kind": "list",
      "text": "~820k people die every year as a consequence despite the availability of effective vaccines and antivirals.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "81bca0c3-b2ef-4ecd-8b7d-974f767f863a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.15,
        "x": 0.6,
        "y": 0.58
      },
      "kind": "paragraph",
      "text": "Low due to sub-optimal SOC cure rate and asymptomatic nature of disease.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "28e2a888-38ee-454b-907f-89b898f94bb4",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.3,
        "x": 0.35,
        "y": 0.92
      },
      "kind": "source-note",
      "text": "Sources: https://www.who.int/news-room/fact-sheets/detail/hepatitis-b; https://www.hepb.org/what-is-hepatitis-b/what-is-hepb/facts-and-figures/",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "87a9556f-89fb-497c-b234-85427051457a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.08,
        "w": 0.6,
        "x": 0.07,
        "y": 0.05
      },
      "kind": "title",
      "text": "HBV Presents a Significant Unmet Medical Need",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "24d06433-8226-44aa-b485-cdb9d93b6237",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [
    {
      "name": "funnel",
      "slug": null,
      "matchId": "5c76bd97-b007-4311-8e32-8e55ca671ca9",
      "evidence": "The nested circles represent a patient funnel from total population to treated patients.",
      "confidence": 0.9
    }
  ],
  "arcBeats": [
    {
      "to": 7,
      "from": 7,
      "beatId": "3adfa18e-bbfe-4577-8cc3-d51ef78ca459",
      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Problem",
      "beatSlug": "problem-agitate-solution-problem-identify-pain",
      "evidence": "The document identifies HBV as a significant unmet medical need.",
      "position": 0,
      "confidence": 0.8,
      "parentBeatName": "Complication",
      "parentBeatSlug": "complication"
    },
    {
      "to": 7,
      "from": 7,
      "beatId": "48052fad-de34-4402-80d4-848fa58261ba",
      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Agitate",
      "beatSlug": "problem-agitate-solution-agitate-make-it-worse",
      "evidence": "The document highlights the limitations of current treatments.",
      "position": 1,
      "confidence": 0.8,
      "parentBeatName": "Development",
      "parentBeatSlug": "development"
    }
  ],
  "loops": [
    {
      "to": 7,
      "from": 7,
      "name": "Cost Of Inaction",
      "slug": "27-cost-of-inaction",
      "bestFor": "Urgent budget requests, compliance, risk mitigation",
      "matchId": "cb04ba74-1ad4-41a8-8ee8-d093322ec7b3",
      "evidence": "The document highlights the unmet medical need.",
      "position": 0,
      "objective": "What is the cost of not addressing HBV?",
      "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
      "confidence": 0.6,
      "description": "Quantify what happens if the audience does nothing"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}