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  "documentTitle": "23andMe | Investor Presentation Deck | 39 slides",
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  "presentationDate": "2024-01-01 00:00:00",
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  "notes": "The chart is a dot plot showing odds ratios for various phenotypes related to TSLP.",
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      "text": "We observe a clear genetic signal linking TSLP to asthma. We do not observe signals in phenotypes that would point to safety issues. Amgen clinical trials of anti-TSLP mAb as eczema target failed. We do not observe a statistically significant genetic signal linking TSLP to eczema. We observe a strong genetic signal linking TSLP to eosinophilic esophagitis → potential indication expansion in a rare disease",
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      "text": "23andMe runs GWAS in >1,000 phenotypes. PheWAS (Phenome-Wide Association Study) captures pleiotropic effects of genetic variants and points to possible unwanted toxicities or potential indication expansions",
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      "text": "PheWAS: Breadth of Phenotyping Elucidates Critical Disease Drivers",
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