{
  "docId": "019de076-87a3-715f-b988-6da9cfb3fd56",
  "docSlug": "560176b410a72a6b2e67af5dd2a20758",
  "documentTitle": "NeuroSense Therapeutics | Investor Presentation Deck | 33 slides",
  "authorId": "neurosense-therapeutics",
  "authorName": "NeuroSense Therapeutics",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2023-12-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 25,
  "pageCount": 33,
  "prevPage": 24,
  "nextPage": 26,
  "slideType": "traction",
  "function": "show_traction",
  "density": "dense",
  "nDataPoints": 6,
  "notes": "The slide presents clinical biomarker data (Aβ40, Aβ42, Tau, pTau, PgJ2) comparing control vs AD groups, analyzed via Mann-Whitney U test.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de076-87a3-715f-b988-6da9cfb3fd56/25",
  "deckHref": "/decks/019de076-87a3-715f-b988-6da9cfb3fd56",
  "deckJsonHref": "/decks/019de076-87a3-715f-b988-6da9cfb3fd56.json",
  "deckAnchorHref": "/decks/019de076-87a3-715f-b988-6da9cfb3fd56#slide-25",
  "components": [
    {
      "bbox": {
        "h": 0.65,
        "w": 0.68,
        "x": 0.04,
        "y": 0.25
      },
      "kind": "chart",
      "text": "Six bar charts comparing biomarker levels in Control vs AD groups",
      "attrs": null,
      "subkind": "bar-vertical",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "1980d066-11f3-4107-b3e6-820bddd9d893",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.18,
        "w": 0.22,
        "x": 0.74,
        "y": 0.25
      },
      "kind": "image",
      "text": "Diagram of Neuronal Derived Exosomes",
      "attrs": null,
      "subkind": "infographic",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "7ed2423a-cadc-4ea7-a661-def69a690d98",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.25,
        "w": 0.22,
        "x": 0.74,
        "y": 0.44
      },
      "kind": "paragraph",
      "text": "Biomarkers tested in Neuronal Derived Exosomes comparing non-treated Healthy vs. AD patients, to elucidate the potential target engagement of CogniC.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "1acc6737-1129-4ba9-bc18-8ee1f45f5cbd",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.08,
        "w": 0.6,
        "x": 0.04,
        "y": 0.9
      },
      "kind": "source-note",
      "text": "Biomarker data were analyzed using a Mann-Whitney U test comparing AD samples with controls. *P<0.05, **P<0.01, ***P<0.001",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "5fe38b5e-bd75-4e15-b0d9-24cb8fcfb603",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.15,
        "w": 0.8,
        "x": 0.04,
        "y": 0.04
      },
      "kind": "title",
      "text": "Alzheimer’s (AD) Studies Reveal Potential Effect of NeuroSense’s Combination Therapy",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "81836d73-d5cf-4611-9961-80a78687e593",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "Chartjunk Elimination",
      "slug": "chartjunk-elimination",
      "agent": "Designer",
      "layer": "slide",
      "matchId": "16853686-55aa-4a24-946a-8ad0c099285e",
      "evidence": "Biomarkers tested in Neuronal Derived Exosomes comparing non-treated Healthy vs. AD patients, to elucidate the potential target engagement of CogniC.",
      "confidence": 0.7
    },
    {
      "name": "Data-Ink Ratio",
      "slug": "data-ink-ratio",
      "agent": "Designer",
      "layer": "slide",
      "matchId": "5ac85c2f-32d9-482c-ab48-ac868ec0c9d3",
      "evidence": "Six bar charts comparing biomarker levels in Control vs AD groups",
      "confidence": 0.7
    }
  ],
  "frameworks": [
    {
      "name": "analytical-method",
      "slug": null,
      "matchId": "732da1e7-b014-4df3-92be-b81547a5fafd",
      "evidence": "Mann-Whitney U test mentioned in source note",
      "confidence": 0.9
    }
  ],
  "arcBeats": [],
  "loops": [
    {
      "to": 25,
      "from": 24,
      "name": "Quick Win Big Bet",
      "slug": "47-quick-win-big-bet",
      "bestFor": "Transformation planning, 100-day plans, resource allocation",
      "matchId": "e681d414-7700-4a5b-99a5-b22bec923cbe",
      "evidence": "The document mentions the potential for PrimeC in Alzheimer's disease, highlighting its broad therapeutic potential.",
      "position": 2,
      "objective": "What is the potential for PrimeC in other neurodegenerative diseases?",
      "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
      "confidence": 0.6,
      "description": "Separate initiatives into immediate wins and longer-term strategic bets"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}