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  "notes": "Includes a table of prevalence/incidence for various indications and a diagram of the JAK-STAT signaling pathway.",
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      "text": "Potential Clinical Activity Based on Preclinical Data: Single agent activity in heme (i.e. CTCL, PTCL, LGL-L); potential activity in solid tumors in combination",
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      "text": "KT-333 is a potent highly selective heterobifunctional small molecule degrader of STAT3; High degree of validation of JAK-STAT pathway; Traditionally undrugged target; First-in-class opportunity.",
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