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  "presentationDate": "2023-11-01 00:00:00",
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  "notes": "The slide displays 12 bar charts representing log2(fold change) for specific genes across individual patients.",
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      "text": "Gene expression bar charts for AD and HS cohorts",
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      "text": "Substantial downregulation of many disease relevant genes in both HS and AD patients. Downregulation exceeded 90% for many genes. Broad anti-inflammatory signature with downregulation of genes responsible for: IL1 family cytokines, Th1, Th17, Th2, Innate immunity",
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      "text": "†log2(fold change): -1 = 50% decrease, -2 = 75% decrease, -3 = 87.5% decrease *Evaluable patients for whom the samples were of sufficient quality for analysis.",
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      "text": "Disease-Relevant Genes Downregulated in Skin Lesions in ≥ 50% of Evaluable* AD (N=7) and HS (N=10) Patients at Day 28 (RNAseq)",
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