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  "documentTitle": "Erasca | Investor Presentation Deck | 56 slides",
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      "kind": "paragraph",
      "text": "ERAS-601 demonstrated no off-target activity in 300 kinase (<30% inhibition @ 1µM) and 12 phosphatase panels (IC50 >10µM)",
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      "text": "RMC-4550 is Revolution Medicine’s SHP2i tool compound and is believed to behave similarly to their clinical compound, RMC-4630 (per company disclosure); LoF = loss of function; wtEGFR = wildtype EGFR",
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      "text": "Biochemical SHP2 inhibition IC50 (nM) for ERAS-601 is 4.6",
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