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  "documentTitle": "Nuvalent | Investor Presentation Deck | 52 slides",
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  "notes": "Includes a spider plot (target lesion change) and a bar chart (allele clearance).",
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      "kind": "chart",
      "text": "Reduction in ROS1 G2032R Allele",
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      "text": "Reduction in Tumor Burden in Cancers with ROS1 G2032R",
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      "text": "Data as of 13 Sep 22, for response-evaluable patients with NSCLC treated by 01 Sep 2022. Source: Drilon A. et al., EORTC-NCI-AACR 2022.",
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      "text": "Each unique color indicates data from the same patient across both figures; PD (due to new lesions); Prior treatments include repotrectinib.",
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      "text": "Subgroup with known ROS1 G2032R resistance mutation: ORR: 78% (7/9); 100% (9/9) with tumor shrinkage. One patient with ROS1 D2033N with ongoing PR (-40%) pending confirmation.",
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      "kind": "title",
      "text": "ROS1 Resistance Mutations | NVL-520 Induced Rapid Responses in TKI-Resistant Patients",
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