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  "notes": "Includes two scientific citations for the mechanism and brain penetration.",
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      "text": "LSD1 demethylates histones, playing a critical role in suppressing the expression of genes required for cellular differentiation. Drives the proliferation and survival of several tumour types. LSD1 is overexpressed in many cancer types across haematology and oncology. e.g., in SCLC, high LSD1 expression is associated with downregulated differentiation pathways. Inhibiting LSD1 reactivates expression of genes driving differentiation; can inhibit cell growth and sensitise any remaining cells to other agents",
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      "text": "Trends Mol Med 2019; 25(4): 261-264; Mol Cell Oncol 2018; 5(4) e1481813; *Int J Gen Med 2021; 14: 10131-9",
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