{
  "docId": "019de075-e64c-773b-a5bd-08e51f7033a7",
  "docSlug": "8122e3ca3ef658190e4851ff70e19f61",
  "documentTitle": "Arbutus Biopharma | Investor Presentation Deck | 25 slides",
  "authorId": "arbutus-biopharma",
  "authorName": "Arbutus Biopharma",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2023-10-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 7,
  "pageCount": 25,
  "prevPage": 6,
  "nextPage": 8,
  "slideType": "problem_statement",
  "function": "frame_problem",
  "density": "dense",
  "nDataPoints": 8,
  "notes": "Uses a geographic map and a nested circle diagram to illustrate the treatment gap.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de075-e64c-773b-a5bd-08e51f7033a7/7",
  "deckHref": "/decks/019de075-e64c-773b-a5bd-08e51f7033a7",
  "deckJsonHref": "/decks/019de075-e64c-773b-a5bd-08e51f7033a7.json",
  "deckAnchorHref": "/decks/019de075-e64c-773b-a5bd-08e51f7033a7#slide-7",
  "components": [
    {
      "bbox": {
        "h": 0.6,
        "w": 0.25,
        "x": 0.75,
        "y": 0.17
      },
      "kind": "diagram",
      "text": "Nested circles showing >290M total, 30M diagnosed, 6.6M treated",
      "attrs": null,
      "subkind": "other",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "e4fc38cd-05ae-4767-8d7e-8afd758cd995",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.6,
        "w": 0.55,
        "x": 0.07,
        "y": 0.25
      },
      "kind": "image",
      "text": "Global map showing HBV prevalence by region",
      "attrs": null,
      "subkind": "map",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "833b9353-f1eb-4843-a818-58e6171d7e79",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.1,
        "x": 0.16,
        "y": 0.95
      },
      "kind": "legend",
      "text": "SOC: Standard of Care",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "d9c54449-17c8-44e6-9a1f-3e0d61ab1274",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.15,
        "x": 0.07,
        "y": 0.7
      },
      "kind": "paragraph",
      "text": "~820k people die every year as a consequence despite the availability of effective vaccines and antivirals.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "5fbf6e46-7463-46e3-974b-697317d4041d",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.15,
        "x": 0.07,
        "y": 0.17
      },
      "kind": "paragraph",
      "text": ">290M people are chronically infected with HBV, globally.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "6bdce22f-9abe-47aa-8f77-6df3aace50be",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.3,
        "x": 0.37,
        "y": 0.92
      },
      "kind": "source-note",
      "text": "Sources: https://www.who.int/news-room/fact-sheets/detail/hepatitis-b https://www.hepb.org/what-is-hepatitis-b/what-is-hepb/facts-and-figures/",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "351e1966-2f73-4af9-b825-f359fda57c81",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.06,
        "w": 0.7,
        "x": 0.07,
        "y": 0.06
      },
      "kind": "title",
      "text": "HBV Presents a Significant Unmet Medical Need",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "b81d7d39-a586-4657-97ec-dd2c63ef5130",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "Audience Definition",
      "slug": "audience-definition",
      "agent": "Storyteller",
      "layer": "slide",
      "matchId": "317f5822-90b8-4d28-96f8-25c434f111c1",
      "evidence": "Global map showing HBV prevalence by region",
      "confidence": 0.5
    },
    {
      "name": "Problem Statement Canvas",
      "slug": "problem-statement-canvas",
      "agent": "Architect",
      "layer": "slide",
      "matchId": "97842bb3-917b-4179-ad8c-0fee14ef6498",
      "evidence": "HBV Presents a Significant Unmet Medical Need",
      "confidence": 0.7
    }
  ],
  "frameworks": [
    {
      "name": "market-segmentation-pyramid",
      "slug": null,
      "matchId": "ebc41d86-fa23-4bf2-84e0-f2608ba7ae07",
      "evidence": "Nested circles representing the funnel from total population to treated patients",
      "confidence": 0.8
    }
  ],
  "arcBeats": [
    {
      "to": 7,
      "from": 6,
      "beatId": "1fd38620-0355-494b-8110-485e59feaa7e",
      "arcName": "The Sequoia Pitch",
      "arcSlug": "sequoia-pitch",
      "beatName": "Problem",
      "beatSlug": "sequoia-pitch-problem",
      "evidence": "HBV Overview and HBV Presents a Significant Unmet Medical Need",
      "position": 0,
      "confidence": 0.8,
      "parentBeatName": "Complication",
      "parentBeatSlug": "complication"
    }
  ],
  "loops": [
    {
      "to": 8,
      "from": 7,
      "name": "Cost Of Inaction",
      "slug": "27-cost-of-inaction",
      "bestFor": "Urgent budget requests, compliance, risk mitigation",
      "matchId": "76882cac-b39a-4c73-bd50-681a12eb8cde",
      "evidence": "HBV Presents a Significant Unmet Medical Need, Therapeutic success will require a combination of agents",
      "position": 0,
      "objective": "highlight the need for effective HBV treatment",
      "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
      "confidence": 0.7,
      "description": "Quantify what happens if the audience does nothing"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}