{
  "docId": "019de075-e64c-773b-a5bd-08e51f7033a7",
  "docSlug": "8122e3ca3ef658190e4851ff70e19f61",
  "documentTitle": "Arbutus Biopharma | Investor Presentation Deck | 25 slides",
  "authorId": "arbutus-biopharma",
  "authorName": "Arbutus Biopharma",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2023-10-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 6,
  "pageCount": 25,
  "prevPage": 5,
  "nextPage": 7,
  "slideType": "context",
  "function": "establish_context",
  "density": "dense",
  "nDataPoints": 1,
  "notes": "The slide uses a four-column layout to structure the disease overview.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de075-e64c-773b-a5bd-08e51f7033a7/6",
  "deckHref": "/decks/019de075-e64c-773b-a5bd-08e51f7033a7",
  "deckJsonHref": "/decks/019de075-e64c-773b-a5bd-08e51f7033a7.json",
  "deckAnchorHref": "/decks/019de075-e64c-773b-a5bd-08e51f7033a7#slide-6",
  "components": [
    {
      "bbox": {
        "h": 0.3,
        "w": 0.22,
        "x": 0.76,
        "y": 0.23
      },
      "kind": "list",
      "text": "Rationale: Need for finite/efficacious treatments; Combination therapy required to boost immune system.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "139b1f04-3ef1-42d0-9a38-a4a1f9dfd418",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.3,
        "w": 0.22,
        "x": 0.52,
        "y": 0.23
      },
      "kind": "list",
      "text": "Treatments: NA therapy (lifelong); Peg-IFNα (poorly tolerated); <5% achieve functional cure.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "c53bc4ef-2121-4a2b-8737-82c624dd16c6",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.3,
        "w": 0.22,
        "x": 0.04,
        "y": 0.23
      },
      "kind": "list",
      "text": "Cause & Symptoms: Life-threatening liver infection; Transmitted through body fluids; Long-term chronic infection leads to cirrhosis/cancer.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "d0106515-5a71-4ee9-98d5-05bc59c329ac",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.3,
        "w": 0.22,
        "x": 0.28,
        "y": 0.23
      },
      "kind": "list",
      "text": "Diagnosis: HBsAg detection; Additional biomarkers necessary.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "f19126f8-3807-4607-9af2-df0221ba7f23",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.7,
        "x": 0.05,
        "y": 0.83
      },
      "kind": "source-note",
      "text": "Sources: WHO, Hep B Foundation, Kowdley et al. (2012), Package Inserts.",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "70cd57a2-dff2-4dc3-a524-482862f726dd",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.06,
        "w": 0.28,
        "x": 0.077,
        "y": 0.06
      },
      "kind": "title",
      "text": "HBV Overview",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "24d3ead9-37fc-49a5-86df-d89fcbc5f59d",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 7,
      "from": 6,
      "beatId": "1fd38620-0355-494b-8110-485e59feaa7e",
      "arcName": "The Sequoia Pitch",
      "arcSlug": "sequoia-pitch",
      "beatName": "Problem",
      "beatSlug": "sequoia-pitch-problem",
      "evidence": "HBV Overview and HBV Presents a Significant Unmet Medical Need",
      "position": 0,
      "confidence": 0.8,
      "parentBeatName": "Complication",
      "parentBeatSlug": "complication"
    },
    {
      "to": 6,
      "from": 6,
      "beatId": "ffc17fa1-4375-4add-a7ea-7b04e5fc7a17",
      "arcName": "The Sequoia Pitch",
      "arcSlug": "sequoia-pitch",
      "beatName": "Market Size",
      "beatSlug": "sequoia-pitch-market-size",
      "evidence": "HBV Overview",
      "position": 3,
      "confidence": 0.8,
      "parentBeatName": "Evidence",
      "parentBeatSlug": "evidence"
    }
  ],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}