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  "documentTitle": "Alkermes | Results Presentation Deck | 27 slides",
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  "notes": "Includes box plots for AUC and Cmax across dose levels (1, 3, 8, 15, 25, 50 mg).",
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      "text": "Overall PK profile supports once-daily dosing; Mimics natural sleep/wake cycle; Half life = 8-10 hours. Wide safety margin; ~100-fold safety multiples. 2 metabolites measured; Consistent with preclinical; No pharmacologic activity.",
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      "text": "Toxicology studies in mice up to 28 days of dosing completed; AUC: area under the curve; PK: pharmacokinetics",
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      "text": "ALKS 2680 Achieved Desired Pharmacokinetic Profile With Once-Daily Dosing",
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