{
  "docId": "019de075-e061-72f9-baa2-90171b05eced",
  "docSlug": "cdaaa50efb264b4a4093f665bafb20a4",
  "documentTitle": "Absci | Investor Presentation Deck | 111 slides",
  "authorId": "absci",
  "authorName": "Absci",
  "documentKindSlug": "conference-presentation",
  "documentKindLabel": "Conference presentation",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2023-10-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 102,
  "pageCount": 111,
  "prevPage": 101,
  "nextPage": 103,
  "slideType": "key_takeaways",
  "function": "analyze_data",
  "density": "dense",
  "nDataPoints": 2,
  "notes": "Includes a Kaplan-Meier survival curve and a biological diagram of TLS.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de075-e061-72f9-baa2-90171b05eced/102",
  "deckHref": "/decks/019de075-e061-72f9-baa2-90171b05eced",
  "deckJsonHref": "/decks/019de075-e061-72f9-baa2-90171b05eced.json",
  "deckAnchorHref": "/decks/019de075-e061-72f9-baa2-90171b05eced#slide-102",
  "components": [
    {
      "bbox": {
        "h": 0.3,
        "w": 0.4,
        "x": 0.55,
        "y": 0.3
      },
      "kind": "chart",
      "text": "Kaplan-Meier survival curve comparing High Ig Staining vs Low Ig Staining.",
      "attrs": null,
      "subkind": "line",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "4a68052e-dc97-4612-b7fa-74451398cd8e",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.45,
        "w": 0.45,
        "x": 0.05,
        "y": 0.35
      },
      "kind": "image",
      "text": "Diagram of TLS showing B cells, T cells, plasma cells, and macrophages in a tumor environment.",
      "attrs": null,
      "subkind": "illustration",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "87be3745-f34f-4cce-80f4-bcc4dab2073f",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.25,
        "w": 0.4,
        "x": 0.55,
        "y": 0.65
      },
      "kind": "list",
      "text": "The presence of TLS is associated with longer progression-free survival and better response to immune checkpoint inhibitors. Rapidly growing evidence illustrates correlation between TLS-derived antibodies in the tumor microenvironment and positive clinical outcomes. TLS-derived antibodies have been shown to be associated with apoptosis of cancer cells in patients.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "e0e2f232-a0e3-4c2c-9b8c-b9da866ed840",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.45,
        "x": 0.05,
        "y": 0.85
      },
      "kind": "source-note",
      "text": "Meylan, Maxime, et al. \"Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer.\" Immunity 55.3 (2022): 527-541.",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "82431a76-fab8-40da-9f70-5057c7b6e6f5",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.2,
        "w": 0.92,
        "x": 0.04,
        "y": 0.05
      },
      "kind": "title",
      "text": "Antibodies selected in tertiary lymphoid structures bind to cancer cells and are associated with favorable clinical outcomes",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "f3a1b88b-491f-46ad-9beb-24eb4a3e59ec",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}