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  "documentTitle": "Neumora Therapeutics | IPO Presentation Deck | 32 slides",
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  "authorName": "Neumora Therapeutics",
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  "presentationDate": "2023-09-01 00:00:00",
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  "notes": "Includes a detailed biological mechanism diagram showing the interaction of KOR, dynorphin, and neurotransmitters.",
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      "text": "Strong Biological Rationale: KOR/dynorphin in are important regulators of stress-induced alterations in reward processing, mood states and cognition",
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      "text": "Mechanism of action diagram showing KOR antagonism by NMRA-140 and its effect on neurotransmitters.",
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      "text": "Drug Profile: Oral, once-daily, 80 mg dose. Strong IP Protection: Exclusivity through 2041.",
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      "text": "Pharmacologic Profile: Selective KOR antagonist, >300-fold selectivity, 90% receptor occupancy.",
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      "text": "Potential to be first novel mechanism approved in MDD in decades",
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      "text": "Navacaprant: KOR Antagonism has Potential for Broad Neuropsychiatric Impact",
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