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  "documentTitle": "Aeglea BioTherapeutics | Investor Presentation Deck | 56 slides",
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  "presentationDate": "2023-09-01 00:00:00",
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  "notes": "The chart shows dose-response curves for three donors; the table summarizes the calculated EC50 values.",
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      "text": "PBMCs from three human donors were isolated and stained with either vedolizumab or SPY001, as well as a basic immunophenotyping T-cell panel. Both vedolizumab and SPY001 exhibited binding on the memory T-helper CD3+CD4+CD45RO+ population. EC50 values for both antibodies corresponded well with what has previously been reported for binding to the same population: EC50 ~ 0.3 nM.",
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