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      "text": "Second generation imipridone designed to expand to new indications\nEfficacy in cell culture, xenograft and transgenic central nervous system (CNS) and other tumor models\nOral dose escalation trials ongoing in CNS cancers\nMonotherapy response reported by investigator in early dose escalation cohort for a patient in recurrent non-H3 K27M GBM\nDordaviprone responses amongst CNS tumors exclusively in H3K27M gliomas\nDose level 2 (100mg), once weekly dosing",
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