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  "docSlug": "53c1bfc711678d7524a7d4316a5473e9",
  "documentTitle": "Chimerix | Investor Presentation Deck | 43 slides",
  "authorId": "chimerix",
  "authorName": "Chimerix",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2023-08-01 00:00:00",
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  "pageNumber": 23,
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  "notes": null,
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      "kind": "list",
      "text": "No approved therapies for H3 K27M mutant glioma, ONC201 is the leading program targeting this mutation globally\nPotential market opportunity ~$750 million\nApproximately 5,000 patients in top seven markets\nUltra-orphan indication drug pricing\nH3 K27M mutations most often in children / young adults (little exposure to Medicare)\nLow barriers to adoption\nPatent protection for lead indication into 2037 - potential U.S. patent term extension (up to five years)",
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      "text": "No effective alternative therapies\nHigh unaided awareness among neuro-oncologists\nMutation routinely identified by existing diagnostics\nLonger-term, potentially combinable with other glioma therapies",
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      "kind": "title",
      "text": "H3 K27M-mutant glioma: rapid ramp to peak revenue expected",
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      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Solution",
      "beatSlug": "problem-agitate-solution-solution-provide-relief",
      "evidence": "The deck presents ONC201 as a solution, including its mechanism of action, market opportunity, and development plans",
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      "confidence": 0.8,
      "parentBeatName": "Resolution",
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  "loops": [
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      "name": "Quick Win Big Bet",
      "slug": "47-quick-win-big-bet",
      "bestFor": "Transformation planning, 100-day plans, resource allocation",
      "matchId": "cb576a48-1f93-4d7c-8d9b-075787961712",
      "evidence": "The deck presents ONC201's potential for efficacy and market opportunity",
      "position": 1,
      "objective": "Can ONC201 be a quick win and a big bet for Chimerix?",
      "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
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