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  "documentTitle": "Arbutus Biopharma | Investor Presentation Deck | 28 slides",
  "authorId": "arbutus-biopharma",
  "authorName": "Arbutus Biopharma",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2023-08-01 00:00:00",
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  "pageNumber": 11,
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  "density": "dense",
  "nDataPoints": 84,
  "notes": "Data presented at Global Hepatitis Summit 2023. Includes specific cohort N values and standard error (SE) in parentheses.",
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  "slideHref": "/slides/019de075-746f-7643-8ae7-19646171e75b/11",
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      "kind": "list",
      "text": "All Cohorts achieved at least a -1.8 log10 decline in mean HBsAg at the end of the treatment period (Week 48). Mean HBsAg levels remained below baseline values at Follow Up Week 48. No significant differences between doses.",
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      "text": "Data shown as mean (SE) log10 IU/mL; minimum of 5 subjects/timepoint. Last imdusiran (AB-729) dose Cohort E: Week 44, Cohorts F, I, G, K: Week 40, Cohort J: Week 36; HBsAg Assay LLOQ = 0.07 IU/mL; *N=6; #N=5",
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      "kind": "table",
      "text": "Mean (SE) Baseline and Δ log10 HBsAg by Visit table",
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      "kind": "title",
      "text": "Robust HBsAg Declines Irrespective of Dose, Dosing Schedule, HBeAg or HBV DNA Status",
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      "beatId": "8558af21-b173-40d9-bee7-cbb86e4f3ca4",
      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Solution (Provide relief)",
      "beatSlug": "problem-agitate-solution-solution-provide-relief",
      "evidence": "The deck presents Arbutus Biopharma's pipeline, including Imdusiran, AB-161, and AB-101, as a promising approach to treating HBV",
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      "parentBeatName": "Resolution",
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  "loops": [
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      "name": "Jobs To Be Done",
      "slug": "53-jobs-to-be-done",
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