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  "documentTitle": "Exscientia | Investor Presentation Deck | 73 slides",
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  "presentationDate": "2023-07-01 00:00:00",
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  "notes": "The slide uses a combination of donut charts for sample sizes and bar charts for statistical significance, followed by scatter plots to visualize the inverse correlation.",
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      "text": "Bar charts showing TIS Low vs TIS High for Breast, Pancreas, Kidney, Lung",
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      "text": "Biological validation of ABS in a larger sample cohort (TCGA1): Higher adenosine as determined by ABS correlates to lower inflammation in the tumour as determined by the tumour inflammation signature (TIS). Patients who have high ABS have a low TIS score. TIS is a predictive signature for anti-PD-1 response2",
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      "text": "1. The Cancer Genome Atlas Project (TCGA) dataset, NCI 2. Damotte et al, Journal of Translational Medicine (2019); Vladimer et al, ESMO I-O (2022)",
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      "text": "High ABS correlates with weakened local immune response in microenvironment",
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