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      "text": "ONC201 can selectively induce apoptosis in cancer cells by altering activity of two proteins. DRD2 antagonism: DRD2 is a G protein-coupled neuroreceptor that regulates Ras signaling; ONC201 antagonizes DRD2, inhibiting Ras signaling pathways. ClpP agonism: ClpP normally degrades misfolded proteins in mitochondria; ONC201 modifies ClpP conformation, promoting excess degradation of specific mitochondrial proteins important for cancer cell viability.",
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