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      "text": "No effective alternative therapies\nHigh unaided awareness among neuro-oncologists\nMutation routinely identified by existing diagnostics\nLonger-term, potentially combinable with other glioma therapies",
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      "text": "No approved therapies for H3 K27M mutant glioma, ONC201 is the leading program targeting this mutation globally\nPotential market opportunity ~$750 million\nApproximately 5,000 patients in top seven markets\nUltra-orphan indication drug pricing\nH3 K27M mutations most often in children / young adults (little exposure to Medicare)\nLow barriers to adoption\nPatent protection for lead indication into 2037 - potential U.S. patent term extension (up to five years)",
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