{
  "docId": "019de074-ca9a-70d9-9ba2-1d5f94361fe0",
  "docSlug": "6d754588aa25b32079af055d51113b03",
  "documentTitle": "Aeglea BioTherapeutics | Investor Presentation Deck | 38 slides",
  "authorId": "aeglea-biotherapeutics",
  "authorName": "Aeglea BioTherapeutics",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2023-05-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 12,
  "pageCount": 38,
  "prevPage": 11,
  "nextPage": 13,
  "slideType": "traction",
  "function": "show_traction",
  "density": "dense",
  "nDataPoints": 8,
  "notes": null,
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de074-ca9a-70d9-9ba2-1d5f94361fe0/12",
  "deckHref": "/decks/019de074-ca9a-70d9-9ba2-1d5f94361fe0",
  "deckJsonHref": "/decks/019de074-ca9a-70d9-9ba2-1d5f94361fe0.json",
  "deckAnchorHref": "/decks/019de074-ca9a-70d9-9ba2-1d5f94361fe0#slide-12",
  "components": [
    {
      "bbox": {
        "h": 0.115,
        "w": 0.72,
        "x": 0.14,
        "y": 0.758
      },
      "kind": "callout",
      "text": "Pegtarviliase was Well Tolerated with Adverse Events Primarily Associated with Subcutaneous Route of Administration",
      "attrs": null,
      "subkind": "primary",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "71cdfe41-0f21-4e2d-86b3-d7ab3d9a7cae",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.215,
        "w": 0.378,
        "x": 0.083,
        "y": 0.235
      },
      "kind": "list",
      "text": "Adverse events (AEs) associated with subcutaneous administration\nMajority of AE were Grade 1/2 injection site reactions (ISR) and hypersensitivity reactions (HSR)\nManaged with antihistamines, steroids",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "ce47f930-7e47-4f32-889d-4f02b7dbbaa9",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.473,
        "w": 0.502,
        "x": 0.437,
        "y": 0.219
      },
      "kind": "table",
      "text": "Adverse Events | Participants N=13\nAny treatment-emergent AE | 13 (100%)\nAE leading to discontinuation | 0\nAE leading to dose reduction | 0\nAE of special interest: HSR | 2 (15.3%)\nISR | 10 (76.9%)\nSerious AEs | 1 (7.7%)\nFatal | 0\nRelated | 0",
      "attrs": null,
      "subkind": "data",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "e3c1e221-bcb1-4200-af5c-04bc9a4bbeb7",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.045,
        "w": 0.808,
        "x": 0.068,
        "y": 0.045
      },
      "kind": "title",
      "text": "Interim Results from Phase 1/2 Clinical Trial: Safety Summary",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "bca8751c-ba94-4433-b3ec-c2f886ef0253",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "Table data",
      "slug": "table-data",
      "agent": null,
      "layer": "slide",
      "matchId": "bf66960f-44c4-4055-8527-4044f2c8e93f",
      "evidence": "table/data: Adverse Events | Participants N=13",
      "confidence": 0.7
    }
  ],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 38,
      "from": 3,
      "beatId": "e469074b-5500-4414-8b81-ef0652ee8a7d",
      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Traction",
      "beatSlug": null,
      "evidence": "Slides 3-38 present various traction metrics, including clinical trial results and financial summaries",
      "position": 4,
      "confidence": 0.8,
      "parentBeatName": null,
      "parentBeatSlug": null
    }
  ],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}