{
  "docId": "019de074-a7a3-7510-9ab9-5e74cd7e6c44",
  "docSlug": "8c206fa848e149a61a796c5e8f53c9e1",
  "documentTitle": "Aeglea BioTherapeutics | Investor Presentation Deck | 37 slides",
  "authorId": "aeglea-biotherapeutics",
  "authorName": "Aeglea BioTherapeutics",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2023-04-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 34,
  "pageCount": 37,
  "prevPage": 33,
  "nextPage": 35,
  "slideType": "appendix_methodology",
  "function": "present_framework",
  "density": "dense",
  "nDataPoints": 1,
  "notes": "The slide outlines standard clinical outcome assessments (COAs) for motor function.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de074-a7a3-7510-9ab9-5e74cd7e6c44/34",
  "deckHref": "/decks/019de074-a7a3-7510-9ab9-5e74cd7e6c44",
  "deckJsonHref": "/decks/019de074-a7a3-7510-9ab9-5e74cd7e6c44.json",
  "deckAnchorHref": "/decks/019de074-a7a3-7510-9ab9-5e74cd7e6c44#slide-34",
  "components": [
    {
      "bbox": {
        "h": 0.25,
        "w": 0.55,
        "x": 0.37,
        "y": 0.0018
      },
      "kind": "image",
      "text": "GMFCS levels I-IV illustration",
      "attrs": null,
      "subkind": "illustration",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "ce8deb79-b7c2-4770-b50d-863f1ee91a03",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.25,
        "w": 0.15,
        "x": 0.77,
        "y": 0.007
      },
      "kind": "image",
      "text": "Patient walking with crutches photo",
      "attrs": null,
      "subkind": "photo",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "0aa57926-f5e2-4540-9c1a-b580e1eb6b8a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.2,
        "w": 0.4,
        "x": 0.12,
        "y": 0.0072
      },
      "kind": "image",
      "text": "Patient walking/stair assessment photos",
      "attrs": null,
      "subkind": "photo",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "6e6435de-a382-467b-9655-45f96b4e5f98",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.3,
        "x": 0.55,
        "y": 0.0052
      },
      "kind": "paragraph",
      "text": "Timed Walk Tests",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "4fe76bfb-e5f9-477b-a696-d2dafcaa8f51",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.4,
        "x": 0.04,
        "y": 0.0052
      },
      "kind": "paragraph",
      "text": "Measures of Change in Mobility: Gross Motor Function Measure (GMFM) Part E",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "dca173e6-e8e5-434c-97b0-94b1e8380d09",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.15,
        "w": 0.3,
        "x": 0.04,
        "y": 0.00175
      },
      "kind": "paragraph",
      "text": "Classification of Mobility: Gross Motor Function Classification System (GMFCS)",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "fe07031a-0cce-468e-96a7-600e8485251f",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.55,
        "x": 0.22,
        "y": 0.96
      },
      "kind": "source-note",
      "text": "GMFCS graphic adapted with permission from The Royal Children's Hospital Melbourne, Australia",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "7c6e4a2e-7b64-488e-86c6-9c3bb3af161c",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.06,
        "w": 0.75,
        "x": 0.06,
        "y": 0.04
      },
      "kind": "title",
      "text": "Measuring the Functional Impact of Spasticity in ARG1-D",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "b5cc2f12-d541-4457-a84c-e9a3bb169537",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [
    {
      "name": "Maturity Model",
      "slug": null,
      "matchId": "41fd0a04-239b-4ab6-aa38-b8d3851177b6",
      "evidence": "GMFCS levels I-V represent a progression of motor function impairment",
      "confidence": 0.8
    }
  ],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}