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  "documentTitle": "BenevolentAI | Results Presentation Deck | 38 slides",
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  "authorName": "BenevolentAI",
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  "presentationDate": "2023-03-01 00:00:00",
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  "notes": "The slide uses a process-flow style layout to connect study design to efficacy outcomes.",
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      "text": "= Powered endpoints",
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      "text": "Recruitment completed end of 2022; 91 patients randomised 1:1 for BEN-2293:Vehicle; Patients (Inclusion Criteria): Mild-Moderate AD, Baseline vIGA 2-3, Baseline Itch NRS >=4, Atopic dermatitis affecting 1-30% BSA, 18-65 years; Dosing: 7 day washout, 3 day placebo run-in, 1% w/w BEN-2293 twice daily, 28 days on treatment",
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      "text": "Itch: Change from baseline in Pruritus NRS, Time to itch reduction, Fraction of patients achieving itch reduction; Inflammation: Change from baseline in EASI score, Fraction of patients achieving improvement in EASI score, Change from baseline in BSA, Change from baseline in vIGA; Quality of life: Change from baseline in POEM, DLQI, EQ-5D, PROMIS",
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      "text": "BEN-2293 Phase IIa clinical study designed to demonstrate efficacy in mild-moderate Atopic Dermatitis",
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      "kind": "title",
      "text": "STUDY EFFICACY OUTCOMES",
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      "text": "STUDY DESIGN: SAFETY & EFFICACY",
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