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  "notes": "Includes a quote from Keith Nuechterlein and specific Cohen's d effect size metrics.",
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      "text": "Cohen's d* (Symbol Coding): 20 mg: 0.79 40 mg: 0.56 80 mg: 0.38 *Day 4 vs Day 2",
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      "text": "PHASE 2 PoM TRIAL - EFFICACY DATA ON SUB-COMPONENTS OF MATRICS SCALE",
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      "text": "SUMMARY: RL-007",
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      "text": "Symbol coding response is at a level that would correlate with better work/school performance",
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      "text": "Note: CIAS = Cognitive impairment associated with schizophrenia; HVLT = Hopkins Verbal Learning Test; TID = 3x/day dosing; PoC = Proof of Concept, PoM = Proof of Mechanism 1. Unless otherwise indicated herein, ownership percentage based on ownership of securities with voting rights as of September 30th, 2022.",
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      "text": "OWNERSHIP 51.9% PRODUCT (2R, 3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one(L)-(+) tartrate salt oral capsules (RL-007) PHARMACOLOGY GABA/nicotinic modulator PRODUCT FEATURES Pro-cognitive effects demonstrated in two Phase 1 and two Phase 2 trials No drug-related serious adverse events in over 500 study subject exposures INDICATIONS Primary: Cognitive Impairment Associated with Schizophrenia (CIAS) Potential: Autism, Alzheimer's dementia CURRENT STATUS Phase 2a biomarker trial completed in H2'21 Phase 2b FPI in 1Q'23 Phase 2b PoC data expected H2'24 INTELLECTUAL PROPERTY Issued composition of matter, formulation and method of use patents",
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