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  "presentationDate": "2023-03-01 00:00:00",
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      "text": "1. Given every 12 hours for 7 days, GRX-917 was well-tolerated with no dose-limiting toxicities identified up to the highest dose of 300mg\n2. There were no serious adverse events reported nor dose-related discontinuations due to adverse events\n3. Adverse events in both single- and multiple-ascending dose (SAD and MAD) regimens were comparable to placebo-treated subjects\n4. No significant evidence of sedation or other benzodiazepine-like side effects at any doses tested",
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      "text": "Note: TEAE = Treatment-emergent Adverse Event, SAD = Single Ascending Dose, MAD = Multiple Ascending Dose. 1. n = number of subjects reporting at least one TEAE in that category, % = proportion of cohort total. 2. Defined as an adverse event that began after the start of trial medication treatment. 3. Non-exhaustive. Other recorded TEAEs included Upper respiratory tract infection (3%), Rash erythematous (3%), Dysmenorrhoea (3%), Catheter site pain (3%). 4. Of the 565 patients given XANAX in Ph.3 placebo-controlled trials for anxiety disorders, 41% reported drowsiness versus 22% of those administered placebo (as reported in XANAX FDA label)",
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      "text": "GRX-917 Phase 1 MAD study safety data table showing TEAEs by dose group",
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      "text": "GRX-917 Phase 1 data: No severe or serious adverse events, with minimal sedation or dizziness, confirms favourable safety profile",
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