{ "docId": "019de074-704c-735b-b7a3-613838aa1bf3", "docSlug": "9b81d8a09c69afc3f139dc970effabde", "documentTitle": "Aeglea BioTherapeutics | Investor Presentation Deck | 39 slides", "authorId": "aeglea-biotherapeutics", "authorName": "Aeglea BioTherapeutics", "documentKindSlug": "pitchdeck", "documentKindLabel": "Pitch deck", "sourceTypeSlug": "investor_relations", "sourceTypeLabel": "Investor relations", "presentationDate": "2023-03-01 00:00:00", "orientation": "landscape", "aspectRatio": 1.7777778, "pageNumber": 2, "pageCount": 39, "prevPage": 1, "nextPage": 3, "slideType": "appendix_disclosure", "function": "other", "density": "dense", "nDataPoints": 0, "notes": null, "elementsJson": null, "metadataConfidence": 1, "imagePath": null, "slideHref": "/slides/019de074-704c-735b-b7a3-613838aa1bf3/2", "deckHref": "/decks/019de074-704c-735b-b7a3-613838aa1bf3", "deckJsonHref": "/decks/019de074-704c-735b-b7a3-613838aa1bf3.json", "deckAnchorHref": "/decks/019de074-704c-735b-b7a3-613838aa1bf3#slide-2", "components": [ { "bbox": { "h": 0.205, "w": 0.864, "x": 0.068, "y": 0.715 }, "kind": "disclaimer", "text": "Moreover, we operate in a very competitive and rapidly changing environment, and new risks may emerge from time to time. It is not possible for our management to predict all risks, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements we may make. In light of these risks, uncertainties and assumptions, the forward-looking events and circumstances discussed herein may not occur and actual results could differ materially and adversely from those anticipated or implied in the forward-looking statements. Further information on these and other factors that could affect these forward-looking statements is contained in our most recent Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission (SEC) and other reports filed by the SEC. You should not rely upon forward-looking statements as predictions of future events. Although our management believes that the expectations reflected in our forward-looking statements are reasonable, we cannot guarantee that the future results, levels of activity, performance or events and circumstances described in the forward-looking statements will be achieved or occur. We undertake no obligation to publicly update any forward-looking statements, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "0d11690c-e6ee-4f7c-a14a-c8462034bc3b", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.155, "w": 0.864, "x": 0.068, "y": 0.181 }, "kind": "disclaimer", "text": "This presentation and the accompanying oral presentation contain “forward-looking” statements that are based on our management’s beliefs and assumptions and on information currently available to management. Forward-looking statements include all statements other than statements of historical fact contained in this presentation, including information concerning our current and future financial performance, business plans and objectives, current and future clinical and preclinical development activities, timing and success of our ongoing and planned clinical trials and related data, the timing of announcements, updates, results of our clinical trials and related data, our ability to obtain and maintain regulatory approval, the potential therapeutic benefits, safety profile and economic value of our product candidates, potential growth opportunities, financing plans, use and adequacy of financing plans, the length of time that we believe our existing cash resources will fund operations, competitive position, industry environment and potential market opportunities.", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "16ac1b32-3294-4172-a757-ded71708d02f", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.385, "w": 0.864, "x": 0.068, "y": 0.343 }, "kind": "disclaimer", "text": "Forward-looking statements are subject to known and unknown risks, uncertainties, assumptions and other factors including, but not limited to, those related to the success, cost and timing of our product candidate development activities and ongoing and planned clinical trials; our plans to develop and commercialize targeted therapeutics, including our lead product candidates pegzilarginase and pegtarviliase and our other product candidates; the design, progress of patient enrollment and dosing in our clinical trials; the ability to obtain and maintain regulatory approvals; our ability to obtain funding for our operations, development and commercialization of our product candidates; the expected impact of macroeconomic conditions, including inflation and rising interest rates, on our operations and clinical development activities; the timing of and our ability to obtain regulatory approvals; our ability to obtain regulatory approval for, and commercialize, pegzilarginase, and recognize milestone and royalty payments under our licensing and supply agreement with Immedica; the potential for expedited development and review of pegtarviliase and pegzilarginase as a result of their regulatory designations; the number of possible treatment candidates in potential addressable markets of our product candidates; the rate and degree of market acceptance and clinical utility of our product candidates; the size and growth potential of the markets for our product candidates, and our ability to serve those markets; our commercialization, marketing and manufacturing capabilities and strategy; future agreements with third parties in connection with the potential commercialization of our product candidates; our expectations regarding our ability to obtain and maintain intellectual property protection; our dependence on third party manufacturers; our ability to develop our own commercial manufacturing facility; the success of competing therapies that are or may become available; our ability to attract and retain key scientific or management personnel; and our estimates regarding expenses, future revenue, capital requirements, the length of time that we believe our existing cash resources will fund operations, and needs for additional financing.", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "90e889ac-cbea-43d3-b9d1-c0e97e609dad", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.038, "w": 0.355, "x": 0.068, "y": 0.048 }, "kind": "title", "text": "Forward Looking Statements", "attrs": null, "subkind": "headline", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6501b530-dc41-4f62-a828-fec39c7ae677", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [], "frameworks": [], "arcBeats": [], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }