{
  "docId": "019de074-48ca-708b-9817-9b094467f30f",
  "docSlug": "b3581031b12373a5077a05b88a8907f5",
  "documentTitle": "AstraZeneca | Results Presentation Deck | 45 slides",
  "authorId": "astrazeneca",
  "authorName": "AstraZeneca",
  "documentKindSlug": "conference-presentation",
  "documentKindLabel": "Conference presentation",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2023-02-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 19,
  "pageCount": 45,
  "prevPage": 18,
  "nextPage": 20,
  "slideType": "key_messages",
  "function": "present_solution",
  "density": "overcrowded",
  "nDataPoints": 3,
  "notes": "Includes a visual representation of antibody-drug conjugate mechanism on the left.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de074-48ca-708b-9817-9b094467f30f/19",
  "deckHref": "/decks/019de074-48ca-708b-9817-9b094467f30f",
  "deckJsonHref": "/decks/019de074-48ca-708b-9817-9b094467f30f.json",
  "deckAnchorHref": "/decks/019de074-48ca-708b-9817-9b094467f30f#slide-19",
  "components": [
    {
      "bbox": {
        "h": 0.7,
        "w": 0.13,
        "x": 0.03,
        "y": 0.22
      },
      "kind": "image",
      "text": "Molecular illustration of antibody-drug conjugate",
      "attrs": null,
      "subkind": "illustration",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "0e250a99-b997-4899-82b5-689a79295853",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.05,
        "x": 0.729,
        "y": 0.751
      },
      "kind": "metric",
      "text": "n= 740",
      "attrs": null,
      "subkind": "big-number",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "55626214-b785-47ed-bb27-40d4b39fc25a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.05,
        "x": 0.729,
        "y": 0.418
      },
      "kind": "metric",
      "text": "n= 975",
      "attrs": null,
      "subkind": "big-number",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "d206ebbe-6ae5-4c02-807c-29527d77c6ca",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.05,
        "x": 0.302,
        "y": 0.548
      },
      "kind": "metric",
      "text": "n= 1000",
      "attrs": null,
      "subkind": "big-number",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "fbd9926f-6a49-4935-8f8e-f30fd97a24a7",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.25,
        "x": 0.22,
        "y": 0.26
      },
      "kind": "paragraph",
      "text": "Dato-DXd AVANZAR Phase III",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "08987056-c80c-4366-a90a-4e7de1693605",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.3,
        "x": 0.61,
        "y": 0.26
      },
      "kind": "paragraph",
      "text": "Dato-DXd TROPION-Lung07 Phase III",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "3ea660a3-801a-45f9-8230-f1b0ed8701a4",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.3,
        "x": 0.61,
        "y": 0.59
      },
      "kind": "paragraph",
      "text": "Dato-DXd TROPION-Lung08 Phase III",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "f2967a37-f243-4e97-b334-4d783d060769",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.8,
        "x": 0.03,
        "y": 0.94
      },
      "kind": "source-note",
      "text": "Dato-DXd = datopotamab deruxtecan; IO = immunotherapy; NSCLC = non-small cell lung cancer; PD-L1 = programmed death-ligand 1; TROP2 = trophoblast cell surface antigen 2; PFS = progression-free survival; OS = overall survival; ITT = intent-to-treat; CTx = chemotherapy. Collaboration partners: Daiichi Sankyo (Dato-DXd).",
      "attrs": {
        "numbered": true
      },
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "a1ef9da7-6327-417e-85f8-7a3bee095302",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.04,
        "w": 0.9,
        "x": 0.03,
        "y": 0.13
      },
      "kind": "title",
      "text": "Dato-DXd: Phase III combination trials address unmet need in 1st-line IO-sensitive NSCLC",
      "attrs": null,
      "subkind": "action-title",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "9e3e13ee-19bf-4176-b4ea-f9f5c532c9d1",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.06,
        "w": 0.45,
        "x": 0.03,
        "y": 0.06
      },
      "kind": "title",
      "text": "Oncology: R&D highlights",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "891251a5-a75e-4968-9388-de711e098cf9",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 20,
      "from": 9,
      "beatId": "18107eda-4090-473e-bbf4-20d9925bf6b3",
      "arcName": "Monroe's Motivated Sequence",
      "arcSlug": "monroes-sequence",
      "beatName": "Satisfaction",
      "beatSlug": "monroes-sequence-satisfaction",
      "evidence": "The deck provides detailed information on financial results, oncology performance, and pipeline progress to satisfy the audience's need for information",
      "position": 2,
      "confidence": 0.8,
      "parentBeatName": "Turn",
      "parentBeatSlug": "turn"
    }
  ],
  "loops": [
    {
      "to": 20,
      "from": 5,
      "name": "Logic Chain",
      "slug": "01-logic-chain",
      "bestFor": "Skeptical audiences, controversial recommendations, rigorous analysis",
      "matchId": "6bc4b448-942a-484e-8a92-bc0a89369cb4",
      "evidence": "The deck presents a logical chain of information to support the company's growth prospects",
      "position": 0,
      "objective": "To demonstrate the company's growth potential",
      "structure": "Premise 1 (Accepted truth) -> Premise 2 (Observed fact) -> Therefore... (Inevitable conclusion)",
      "confidence": 0.7,
      "description": "Build an airtight chain of logic where each premise leads inevitably to the conclusion"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}