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      "text": "Ampreloxetine showed biologically driven target engagement\nAmpreloxetine raised circulating NE levels and reduced biomarker of intraneuronal NE metabolism (DHPG)\nIncreases in standing BP after randomized withdrawal were most pronounced in patients with MSA\nIncreasing bioavailability of NE with ampreloxetine may be particularly beneficial in patients with MSA",
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